International Physiology Journal

International Physiology Journal

International Physiology Journal – Aim And Scope

Open Access & Peer-Reviewed

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Aims & Scope

International Physiology Journal (IPJ) publishes mechanistic research on how biological systems function across all organizational levels-from molecular and cellular processes to integrated organ and systemic physiology.
Mechanistic Studies Cellular Physiology Systems Integration Homeostatic Regulation Comparative Physiology

Core Research Domains

Cellular & Molecular Physiology

  • Ion channel function and membrane transport mechanisms
  • Signal transduction pathways in physiological contexts
  • Cellular metabolism and bioenergetics
  • Protein structure-function relationships in physiological processes
  • Gene expression regulation in cellular homeostasis
  • Organelle function and intracellular communication
Typical Fit Example
"Mechanistic analysis of calcium-activated potassium channel regulation in vascular smooth muscle cells during hypoxia"

Systems & Integrative Physiology

  • Cardiovascular system regulation and hemodynamics
  • Respiratory mechanics and gas exchange physiology
  • Renal function and fluid-electrolyte homeostasis
  • Gastrointestinal motility and secretion mechanisms
  • Endocrine system integration and hormonal regulation
  • Multi-organ system interactions and feedback loops
Typical Fit Example
"Integrated cardiovascular-renal responses to acute volume expansion: role of atrial natriuretic peptide in sodium homeostasis"

Neurophysiology & Sensory Systems

  • Neural circuit function and synaptic transmission
  • Sensory transduction mechanisms (vision, audition, chemosensation)
  • Motor control and neuromuscular physiology
  • Autonomic nervous system regulation
  • Neural plasticity and adaptation mechanisms
  • Central pattern generators and rhythmic behaviors
Typical Fit Example
"Synaptic mechanisms underlying respiratory rhythm generation in the pre-Bötzinger complex"

Comparative & Environmental Physiology

  • Physiological adaptations across species and taxa
  • Environmental stress responses (temperature, hypoxia, salinity)
  • Evolutionary physiology and adaptive mechanisms
  • Metabolic scaling and allometry
  • Ecological physiology and organism-environment interactions
  • Physiological diversity in extreme environments
Typical Fit Example
"Comparative analysis of hypoxia tolerance mechanisms in high-altitude versus sea-level vertebrates: role of hemoglobin-oxygen affinity"

Secondary Focus Areas

Exercise & Metabolic Physiology

Physiological responses to physical activity, metabolic adaptations to exercise stress, muscle energetics, and cardiovascular-respiratory integration during exercise.

Developmental Physiology

Ontogenetic changes in physiological systems, maturation of organ function, developmental plasticity, and critical periods in physiological development.

Aging Physiology

Age-related changes in physiological function, mechanisms of physiological decline, cellular senescence effects on organ systems, and homeostatic capacity across lifespan.

Physiological Genomics

Genomic, transcriptomic, and proteomic approaches to understanding physiological regulation, gene-environment interactions, and molecular basis of physiological traits.

Computational Physiology

Mathematical modeling of physiological systems, computational simulations of organ function, systems biology approaches, and predictive physiological models.

Microbial Physiology

Bacterial, viral, and fungal physiological processes, microbial metabolism, host-microbe physiological interactions, and microbial adaptation mechanisms.

Emerging & Frontier Areas

Selective Consideration - Additional Editorial Review

AI-Enhanced Physiological Analysis: Machine learning applications for pattern recognition in physiological data, predictive modeling of system responses
Organ-on-Chip Systems: Microfluidic models of organ physiology, in vitro physiological systems, biomimetic platforms for mechanistic studies
Single-Cell Physiology: High-resolution physiological measurements at single-cell level, cellular heterogeneity in physiological responses
Chronophysiology: Circadian regulation of physiological systems, temporal organization of organ function, biological rhythms and homeostasis
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Article Types & Editorial Priorities

Priority 1

Fast-Track Review (14-21 days to first decision)

Priority 2

Standard Review (21-35 days to first decision)

Rarely Considered

Requires Exceptional Scientific Merit

Editorial Standards & Requirements

Reporting Guidelines

  • ARRIVE 2.0 for animal studies
  • STROBE for observational studies
  • PRISMA for systematic reviews
  • CONSORT for experimental designs
  • MIQE for qPCR experiments

Data Transparency

  • Raw data deposition required
  • Code availability for computational work
  • Protocols shared via protocols.io or similar
  • Materials availability statement
  • Statistical analysis transparency

Ethics & Integrity

  • IACUC/ethics approval for animal work
  • IRB approval if human subjects involved
  • Conflict of interest disclosure
  • Funding source transparency
  • Author contribution statements

Preprint & Prior Publication

  • Preprints encouraged (bioRxiv, medRxiv)
  • Conference abstracts acceptable
  • Thesis chapters considered
  • No duplicate publication
  • Transparent reporting of prior dissemination

Editorial Decision Metrics

18 days
Median Time to First Decision
42%
Acceptance Rate
4 days
Time to Publication
Open
Access Model