Schizophrenia is a chronic and severe psychiatric disorder characterized by disturbances in thought, perception, emotion, and behavior. Its clinical presentation comprises positive symptoms such as delusions, hallucinations, and disorganized thought and speech; negative symptoms including diminished motivation, blun…
Schizophrenia is a chronic and severe psychiatric disorder characterized by disturbances in thought, perception, emotion, and behavior. Its clinical presentation comprises positive symptoms such as delusions, hallucinations, and disorganized thought and speech; negative symptoms including diminished motivation, blunted affect, and social withdrawal; and cognitive impairments affecting attention, working memory, and executive function. The disorder is understood to arise from complex interactions between genetic susceptibility and environmental factors, with dysregulation of dopaminergic and other neurotransmitter systems and abnormalities of neurodevelopment and brain connectivity implicated in its pathophysiology. Onset typically occurs in late adolescence or early adulthood, and the course is often persistent, with substantial effects on functioning and quality of life. Research relevant to this topic includes the metabolic consequences of antipsychotic treatment and the prevalence of metabolic syndrome in patients with schizophrenia, the gastrointestinal health of affected individuals and arguments for nutrition-based intervention, and broader considerations of mental health, perception, and hallucinatory phenomena. Management combines antipsychotic pharmacotherapy with psychosocial, rehabilitative, and supportive interventions, alongside attention to physical health comorbidities frequently associated with the illness and its treatment. Continued study of its biological and clinical dimensions aims to improve early recognition, treatment response, and long-term outcomes.
6 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 6 articles above have been cited 7 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Schizophrenia Disorder, linking to each citing work.