Proteomics and Genomics in Microbial Research

Overview

Proteomics and genomics in microbial research are integrated molecular approaches used to study the genetic content and protein expression of microorganisms, including bacteria, fungi, parasites, and viruses. Genomics examines the complete genetic material of a microbe, its DNA sequence, gene organization, and variation, providing the blueprint of metabolic capabilities, virulence factors, and adaptive potential. Proteomics complements this by characterizing the full set of proteins actually expressed under given conditions, capturing abundance, post-translational modification, and interaction, and thereby revealing the functional and physiological state of the cell that genome sequence alone cannot specify. Together they offer a comprehensive view of the genetic and biochemical networks operating within microbial cells and communities. In microbial research these methods support identification and typing of organisms, elucidation of pathogenic mechanisms and host-pathogen interactions, discovery of molecular biomarkers, and analysis of antimicrobial resistance and metabolic pathways, with proteomic strategies such as label-free shotgun mass spectrometry applied to organisms including parasitic pathogens. The integration of genomic and proteomic data, supported by bioinformatics, underpins applications in diagnostics, drug and vaccine development, and personalized and precision medicine. As sequencing and mass-spectrometry technologies and computational tools continue to advance, proteomics and genomics increasingly resolve the molecular detail of microbial life, informing both fundamental microbiology and translational efforts to detect, treat, and control infection.

Research published in this journal

8 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 8 articles above have been cited 20 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

• Peripheral biomarkers of neuroinflammation in Alzheimer’s disease and vascular dementia
  2026 · Biochemical Pharmacology
• Association of peripheral blood NLRP3, sTREM2, and p-tau217 levels with cognitive outcomes in patients with chronic alcohol-related brain damage
  2026 · Alcohol and Alcoholism
• Chronic alcohol consumption induces phenotypic and functional alterations consistent with a hyper-inflammatory state in peripheral blood mononuclear cell-derived microglia in a rhesus macaque model
  Hami Hemati et al. · 2025 · Brain, behavior, and immunity
• Visible-light-driven oxidative coupling of arylhydrazines with sulfinates catalyzed by polyoxometalates for aryl sulfone synthesis
  2025 · Chemical Communications
• Chronic alcohol consumption induces phenotypic and functional alterations consistent with a hyper-inflammatory state in peripheral blood mononuclear cell-derived microglia in a rhesus macaque model
  2025 · Brain Behavior and Immunity
• Visible-Light-Driven Oxidative Coupling of Arylhydrazines with Sulfinates Catalyzed by Polyoxometalates for Aryl Sulfone Synthesis
  2025 · Chemical Communications
• CRISPR/Cas9 Ribonucleoprotein-Based Genome Editing Methodology in the Marine Protozoan Parasite Perkinsus marinus
  2021 · Frontiers in Bioengineering and Biotechnology
• Colpodella sp. (ATCC 50594) Life Cycle: Myzocytosis and Possible Links to the Origin of Intracellular Parasitism
  2021 · Tropical Medicine and Infectious Disease

A sample of recent works citing this journal's research on Proteomics and Genomics in Microbial Research, linking to each citing work.

This page summarises published research for orientation; it is not medical or professional advice.

Related topics