Research Topic · Peer-Reviewed

Hyperlipidemia

Hyperlipidemia is a metabolic condition defined by elevated concentrations of lipids in the blood, principally cholesterol, triglycerides, or both, carried in lipoprotein particles such as low-density lipoprotein (LDL) and very-low-density lipoprotein. It may be primary, arising from genetic defects in lipid metabol…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 80× across the literature 🔖 ISSN 2574-450X 🗓 Reviewed July 2026

Overview

Hyperlipidemia is a metabolic condition defined by elevated concentrations of lipids in the blood, principally cholesterol, triglycerides, or both, carried in lipoprotein particles such as low-density lipoprotein (LDL) and very-low-density lipoprotein. It may be primary, arising from genetic defects in lipid metabolism—as in familial combined hyperlipidemia, which clusters with insulin resistance and the metabolic syndrome—or secondary to diet, obesity, diabetes, and sedentary behavior. Excess LDL cholesterol promotes atherogenesis, establishing hyperlipidemia as a major modifiable risk factor for coronary artery disease and stroke. Diagnosis rests on the fasting lipid profile, and management combines dietary modification, weight reduction, and physical activity with pharmacotherapy, most notably statins and other lipid-lowering agents, alongside botanical and nutraceutical approaches under investigation. In the context of obesity, adipose-tissue dysfunction and altered lipid handling link weight gain to dyslipidemic states. Research relevant to this area examines the molecular and metabolic pathogenesis of familial combined hyperlipidemia and its association with metabolic syndrome, hypolipidemic effects of botanical agents compared with atorvastatin in fat-fed models, lipid responses in obesity interventions, and dietary influences on cardiometabolic risk. This peer-reviewed literature reflects the genetic, dietary, and pharmacologic dimensions of disordered blood lipids within the broader management of obesity and cardiometabolic disease.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 80 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Hyperlipidemia, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Obesity Management (ISSN 2574-450X).

Journal editorial board
Amit Surve · United States Paola Aceto · Italy Joseph Fomusi Ndisang · Canada

This page summarises published research for orientation; it is not medical or professional advice.