The presence of numerous complaints of a gastroenterocolitic nature in patients with proven NBZ and CNDP and a sharp regression of these complaints after surgical correction of NBZ and CNDP allows us to conclude that the causes of these pathological manifestations are the failure of the Bauhinia valve and chronic violation of the duodenal patency, and the most adequate surgical aid for elimination of clinical manifestations of reflux disease is bauginoplasty with simultaneous duodenojejunostomy.
Academic Editor: Mohamed Mostafa El-Sayed Abdulla, Consultant in pharmaceutical industries, Egypt.
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Copyright © 2021 Martynov Vladimir Leonidovich
The authors have declared that no competing interests exist.
Cases of failure of the Bauhinia flap (NBZ), the presence of chronic impairment of duodenal patency, reflux gastritis, gastroesophageal reflux disease (GERD) have been known for a long time. However, until now, practical medicine does not have specific data - is it possible the presence of several pathological conditions on the basis of reflux of the contents of the underlying departments into the overlying ones in one patient. The clinical possibilities of simultaneous correction of reflux - enteritis, reflux - gastritis and reflux - esophagitis are also unknown. the general etiopathogenetic links of these conditions are not known. The causal relationship between the gastrointestinal tract (GIT) and some extraintestinal diseases, in particular bronchial asthma and dermatoses, has not been studied. Basically, numerous complaints of a gastroenterocolitic nature are explained by functional changes in the gastrointestinal tract, in particular, the functional form of chronic duodenal obstruction (CDP) and irritable bowel syndrome (IRS). At the same time, both patients and doctors of various specialties are doomed to a long dialogue, since recovery does not occur. According to our data, in most patients with these complaints, 94% of patients have proven NBZ and the anatomical form of CNDP, which is also diagnosed in patients with duodenal ulcer (PU 12 - PC), gastric ulcer (PU), bronchial asthma (BA ), dermatoses 1, 2, 3, 4, 5. Therefore, we concluded that the concept of reflux disease should be understood as the simultaneous presence of the following refluxes in patients: colonic, duodenogastric (DGR), gastroesophageal (GER), which implies their simultaneous correction at all levels 1, 2, 3, 4, 5.
Complaints from Patients with Reflux Disease.
All patients with reflux disease (RB) complained of abdominal pain, of which 57% of the pain were diffuse, in 7% of patients the pain was localized in the right iliac region, in 3% in the right hypochondrium, in 2% in the left iliac region, in 4% - in the left and right iliac regions, in 9% - in the right iliac and right hypochondrium regions, in 16% - in the right and left hypochondrium regions, in 2% - in the left hypochondrium and left iliac regions.
In addition to abdominal pain, patients with RB were worried about other complaints typical of gastrointestinal pathology: - 95% of patients noted rumbling in the abdomen, - 79% - bloating, - 71% - constipation, - 65% - diarrhea, - 86% - loosening of the chair, - 88% - feeling of heaviness in the abdomen after eating, - 83% - nausea, - 87% - belching with air, - 95% - bitterness in the mouth, - 79% - bad breath, - 55% - intolerance to milk and other food.
Rapid fatigue occurred in 92% of patients, and in 58% weight loss. In addition to complaints of a gastroenterocolitic nature, 65% of patients noted increased heart rate, 72% - dizziness, 66% - frequent colds (acute respiratory infections, flu, tonsillitis).
Analyzing the clinical manifestations of gastroenterocolitic nature in patients suffering from PUD, PU 12 PK, BA, dermatoses, we can conclude that these complaints are also found in the overwhelming majority of these groups of patients (Table 1).Table 1. The clinical picture in patients with NBZ and HNDP, YABZh and 12 PCs, BA, dermatoses (in%)
|Clinical manifestations||RB (NBZ, KhNDP) N = 318||YABZH and YAB 12 PC N = 149||BA N = 228||Der-mato-zy N = 54|
|Abdominal heaviness after eating||79||69||81||51|
|Belching with air||80||73||61||53|
|Spitting up food||52||32||45||12|
|Heartburn in the epigastrium||68||80||74||56|
|Heartburn behind the breastbone||68||10||74||56|
|Bitterness in the mouth||73||18||74||15|
|Intolerance to milk and other food||44||17||41||44|
|Rumbling in the stomach||86||80||62||71|
|Darkening in the eyes||66||14||70||58|
Thus, patients with NBZ and CNDP, as well as patients with gastric ulcer and duodenal ulcer, bronchial asthma, dermatoses present numerous complaints of the same type of gastroenterocolitic nature, which suggests that this group of patients has a single etiopathogenesis of these pathological manifestations. This category of patients underwent different volumes of operations: bauginoplasty (BP), bauginoplasty in combination with dissection of Treitz's ligament (BP + PCT), bauginoplasty in combination with duodenojejunostya (BP + DES) - Table 2.Table 2. Clinical picture in patients before and after surgical correction of RB
|Symptoms||NBZ, KhNDP (RB) N = 415||After bauginoplasty N = 68||After bauginoplasty + PCT N = 24||After bauginoplasty + duodenojejunostomy N = 19|
|Stomach pain||415 (one hundred%)||24 (34%) р < 0.0001||8 (35%)p < 0.0001||5 (27%)р < 0,0001|
|Heaviness in the abdomen after eating||327 (79%)||18 (26%)р < 0,0001||6 (25%)р = 0,0006||2 (12%)р < 0,0001|
|Nausea||327 (79%)||12 (18%)р < 0,0001||5 (21%)р = 0,0002||2 (12%)р < 0,0001|
|Burp||322 (80%)||24 (35%)р < 0,0001||9 (38%)р = 0,0038||2 (12%)р < 0,0001|
|Regurgitation||216 (52%)||9 (13%)р < 0,0001||5 (21%)р = 0,0178||1 (5%)р = 0,0015|
|Heartburn||282 (68%)||26 (38%)р = 0,0001||12 (50%)р = 0,1901||2 (12%) р = 0,0003|
|Bitterness in the mouth||303 (64%)||29 (43%)р = 0,001||10 (40%)р = 0,0196||2 (12%)р = 0,0001|
|Constipation||303 (64%)||11 (16%)р < 0,0001||4 (16%)р = 0,0001||2 (12%)р = 0,0001|
|Diarrhea||212 (51%)||14 (21%)р = 0,0002||3 (13%)р = 0,0057||2 (12%)р = 0,0064|
|Relaxation||270 (65%)||17 (25%)р < 0,0001||4 (16%)р = 0,0005||2 (12%)р = 0,0009|
|Intolerance to milk and other food||183 (44%)||10 (18%)р = 0,0001||3 (14%)р = 0,0122||4 (24%)р = 0,1476|
|Fatigue||324 (93%)||15 (22%)р = 0,0004||7 (29%)р =0,0196||3 (18%)р <0,0001|
|Weight loss||224 (54%)||13 (19%)р < 0,0001||4 (17%)р < 0,0073||1 (6%)р < 0,0015|
|Weight loss||317 (75%)||10 (14%)р < 0,0001||3 (14%)р < 0,0001||2 (12%)р < 0,0001|
|Bad breath||324 (78%)||5 (7%)р < 0,0001||3 (14%)р < 0,0001||2 (12%)р < 0,0001|
|Bloating||357 (86%)||10 (15%)р < 0,0001||5 (21%)р < 0,0001||2 (12%)р < 0,0001|
Analyzing the clinical manifestations before and after surgery, one can note a sharp regression of gastroenterocolitic complaints (Table 2). The identified set of complaints depends on the condition of the small and large intestine. Improvement of the condition of patients after PD, PD + PCT, PD + DES confirms the main role of PD in the elimination of this symptom complex. The number of patients who stopped noticing these pathological manifestations increased from 2 to 11 times, depending on various symptoms.
Nevertheless, in a significant number of cases, clinical signs of CNDP remain in patients who underwent only bauginoplasty or bauginoplasty with PCT. So, after such volumes of surgical aid, the severity in the abdomen remained in 26% and 25% of patients, respectively, for the indicated operations, nausea - in 18% and 21%, belching - in 35% and 38%, regurgitation - in 13% and 21%, heartburn - 38% and 50%. Surgical aid in the form of bauginoplasty and duodenojejunostomy turned out to be much more adequate in eliminating the clinical manifestations of CPDP. So, the heaviness in the abdomen after eating remained only in 12% of patients, nausea - in 12%, belching - in 12%, regurgitation - in 5%, heartburn - in 12%.
Thus, the presence of numerous gastroenterocolitic complaints in patients with proven NBZ and CNDP and a sharp regression of these complaints after surgical correction of NBZ and CNDP allows us to conclude that the causes of these pathological manifestations are the failure of the Bauginia valve and chronic violation of duodenal patency, and the most adequate bauginoplasty with simultaneous duodenojejunostomy is a surgical tool for eliminating clinical manifestations of reflux disease.