Overview
Nosocomial infections, also termed healthcare-associated infections, are infections that patients acquire during the course of receiving care in a hospital or other healthcare facility and that were not present or incubating at the time of admission. They are a major cause of morbidity, mortality, and increased healthcare cost, and they can be caused by bacteria, fungi, viruses, and parasites, including organisms such as Candida species and Gram-negative bacteria encountered in clinical settings. The most common categories include urinary tract infections, frequently associated with catheterization and with extended-spectrum beta-lactamase-producing organisms; surgical-site and device- or implant-related infections, such as those involving stents; bloodstream infections; and pneumonia. A defining and escalating challenge is antimicrobial resistance, exemplified by the spread of carbapenem-resistant Klebsiella pneumoniae, which limits treatment options and worsens outcomes. Risk is heightened by invasive procedures, indwelling devices, immunosuppression, prolonged hospitalization, and the selective pressure of antibiotic use. Prevention and control depend on rigorous infection prevention and control practices, including hand hygiene, aseptic technique, environmental and device management, surveillance, and antimicrobial stewardship, with the knowledge, attitudes, and practices of healthcare workers being critical determinants, as demonstrated during the COVID-19 pandemic. Accurate microbiological identification and susceptibility testing guide treatment. Reducing nosocomial infection therefore requires combined clinical, microbiological, and institutional strategies to protect vulnerable patients and curb the emergence of resistant pathogens.
Research published in this journal
8 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Knowledge, Attitudes and Practices towards Infection Prevention Control among Healthcare Workers in Selected Hospitals Located in Karongi district, Rwanda
Infection Prevention and Control in Healthcare Facilities During the Covid-19 Pandemic in Ghana
A Tandem of Rare Complications Due to Stent Infection
A Meningeal Syndrome Revealing A Tetanus in A Togolese: Case Report and Review of the Literature
Investigation of Emerging Risk Factors and Isolation of Potential Pathogenic Bacteria from Domestic Dog Stool in Port Harcourt Metropolis, Niger Delta
Growing Threat Increased Carbapenem-Resistance among Klebsiella pneumoniae; Antibiotic Susceptibility Pattern of Klebsiella pneumoniae in a Tertiary Care Hospital
The Development and Evaluation of A Multiplex Real-Time PCR Assay for the Detection of ESBL Genes in Urinary Tract Infections
How this research is being cited
The 8 articles above have been cited 27 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Health Science Reports
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2026 · Cureus
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2026 · Open Research Europe
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2025 · Antimicrobial Resistance and Infection Control
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2025 · Antimicrobial Resistance & Infection Control
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2024 · PLoS ONE
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Solomon O. Olorunleke et al. · 2024 · PLoS ONE
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2023 · South East European Journal of Cardiology
A sample of recent works citing this journal's research on Nosocomial Infection, linking to each citing work.