Antifungal therapy is the use of agents that kill fungi or inhibit their growth to treat infections caused by yeasts, molds, and dimorphic fungi. Such infections range from superficial disease of the skin, nails, and mucous membranes to invasive and life-threatening conditions affecting the lungs, bloodstream, brain…
Antifungal therapy is the use of agents that kill fungi or inhibit their growth to treat infections caused by yeasts, molds, and dimorphic fungi. Such infections range from superficial disease of the skin, nails, and mucous membranes to invasive and life-threatening conditions affecting the lungs, bloodstream, brain, and other organs, particularly in immunocompromised hosts. Antifungal drugs are grouped by mechanism, including agents that target ergosterol or its biosynthesis in the fungal membrane, those that inhibit synthesis of the cell-wall polysaccharide beta-glucan, and those that interfere with fungal nucleic acid synthesis; naturally derived compounds with antifungal activity are also investigated. Effective treatment depends on accurate identification of the organism, assessment of antifungal susceptibility, the site and severity of infection, and host factors, while the narrow selective targets of fungal cells, drug toxicity, and emerging resistance pose ongoing challenges. The scholarship gathered here reflects these themes, including the surge of mucormycosis in post-viral patients and its contributing factors, phytochemical activity against a Mucorales mold, diagnostic correlates in cryptococcal meningitis, surgical management of invasive aspergillosis, susceptibility of dermatophytes, and fungemia caused by an uncommon yeast. Together these studies illustrate how identification, susceptibility, and clinical context guide antifungal therapy across superficial and invasive fungal disease in diverse patient populations.
6 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 6 articles above have been cited 28 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Antifungal Therapy, linking to each citing work.