Research Topic · Peer-Reviewed

Allergy

Allergy is a hypersensitivity disorder in which the immune system mounts an exaggerated response to normally harmless environmental substances, known as allergens. The classic immediate form is mediated by immunoglobulin E antibodies that bind allergen and trigger mast cells and basophils to release histamine and ot…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 20× across the literature 🔖 ISSN 2640-690X 🗓 Reviewed July 2026

Overview

Allergy is a hypersensitivity disorder in which the immune system mounts an exaggerated response to normally harmless environmental substances, known as allergens. The classic immediate form is mediated by immunoglobulin E antibodies that bind allergen and trigger mast cells and basophils to release histamine and other mediators, producing symptoms within minutes; other reactions are delayed and cell-mediated, such as allergic contact dermatitis driven by T cells. Common manifestations include allergic rhinitis, asthma, urticaria, angioedema, atopic and contact dermatitis, food and drug allergy, and, at its most severe, anaphylaxis. In primary and Family Medicine, allergic conditions are among the most frequently encountered problems, requiring recognition of triggers, assessment of severity, and distinction from non-immune adverse reactions. Diagnosis combines clinical history with skin patch and provocation testing and laboratory measures, and management centres on allergen avoidance, pharmacotherapy, and, where appropriate, immunomodulation, together with preparedness for severe reactions. Research relevant to this area examines drug and contact allergy diagnosed by patch and lymphocyte-stimulation testing, cross-reactive hypersensitivity to NSAIDs and COX-2 inhibitors, food and ingestion-related angioedema and urticaria, and standardization of adverse-drug-event reporting. The journal publishes peer-reviewed research relevant to Family Medicine, including the diagnosis, mechanisms, and management of allergic and hypersensitivity disorders.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 20 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Allergy, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Family Medicine (ISSN 2640-690X).

Journal editorial board
Dr. John P. Bartkowski · United States Dr. Angela Pia Cazzolla · Italy Dr. Ian James Martins · Australia

This page summarises published research for orientation; it is not medical or professional advice.