JNDC Journal of New Developments in Chemistry 2377-2549 Open Access Pub United States JNDC-19-2765 10.14302/issn.2377-2549.jndc-19-2765 research-article Tetrodotoxin (TTX) Time–Resolved Absorption and Resonance FT–IR and Raman Biospectroscopy and Density Functional Theory (DFT) Investigation of Vibronic–Mode Coupling Structure in Vibrational Spectra Analysis Alireza Heidari 1 2 * Jennifer Esposito 1 Angela Caissutti 1 Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604, USA American International Standards Institute, Irvine, CA 3800, USA Corresponding author Zhe-Sheng Chenz 1 Professor, Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John’s University, United States. Alireza Heidari, Faculty of Chemistry, California South University, 14731, Comet St. Irvine, CA 92604, American International Standards Institute, Irvine, CA 3800, USA, Email: Alireza.Heidari@calsu.us

The authors have declared that no competing interests exist.

 14 06 2019 2 3 26 48 04 04 2019 12 06 2019 14 06 2019 © 2019 Alireza Heidari, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. This article is available from http://openaccesspub.org/jndc/article/1109

Tetrodotoxin (TTX) is a potent neurotoxin. Its name derives from Tetraodontiformes, an order that includes pufferfish, porcupinefish, ocean sunfish, and triggerfish; several of these species carry the toxin. Although tetrodotoxin was discovered in these fish and found in several other aquatic animals (e.g., in blue–ringed octopuses, rough–skinned newts, and moon snails), it is actually produced by certain infecting or symbiotic bacteria like Pseudoalteromonas, Pseudomonas, and Vibrio as well as other species found in animals. Parameters such as FT–IR and Raman vibrational wavelengths and intensities for single crystal Tetrodotoxin (TTX)are calculated using density functional theory and were compared with empirical results. The investigation about vibrational spectrum of cycle dimers in crystal with carboxyl groups from each molecule of acid was shown that it leads to create Hydrogen bounds for adjacent molecules. The current study aimed to investigate the possibility of simulating the empirical values. Analysis of vibrational spectrum of Tetrodotoxin (TTX) is performed based on theoretical simulation and FT–IR empirical spectrum and Raman empirical spectrum using density functional theory in levels of F/6–31G*, HF/6–31++G**, MP2/6–31G, MP2/6–31++G**, BLYP/6–31G, BLYP/6–31++G**, B3LYP/6–31G and B3LYP6–31–HEG**. Vibration modes of methylene, carboxyl acid and phenyl cycle are separately investigated. The obtained values confirm high accuracy and validity of results obtained from calculations.

Molecular structure of Tetrodotoxin (TTX) 1–42.

 Vibronic Structure Vibrational Spectra Analysis Density Functional Theory (DFT) Tetrodotoxin (TTX) Non–Focal Functions of Becke Correlation Functions of Lee–Yang–Parr Time–Resolved Absorption and Resonance FT–IR and Raman Biospectroscopy. Introduction

Tetrodotoxin (TTX) is a potent neurotoxin. Its name derives from Tetraodontiformes, an order that includes pufferfish, porcupinefish, ocean sunfish, and triggerfish; several of these species carry the toxin. Although tetrodotoxin was discovered in these fish and found in several other aquatic animals (e.g., in blue–ringed octopuses, rough–skinned newts, and moon snails), it is actually produced by certain infecting or symbiotic bacteria like Pseudoalteromonas, Pseudomonas, and Vibrio as well as other species found in animals. Density Functional Theory (DFT) is one of the most powerful calculation methods for electronic structures 1234567. Numerous results have been previously studied and indicate successful use of these methods 8910. The theory is one of the most appropriate methods for simulating the vibrational wavenumbers, molecular structure as well as total energy. It may be useful to initially consider the calculated results by density functional theory using F/6–31G*, HF/6–31++G**, MP2/6–31G, MP2/6–31++G**, BLYP/6–31G, BLYP/6–31++G**, B3LYP/6–31G and B3LYP6–31–HEG** approach 111213141516. It should be noted that calculations are performed by considering one degree of quantum interference as well as polarization effects of 2d orbitals in interaction 17181920212223242526272829303132333435363738394041424344454647.

Tetrodotoxin (TTX) is a tropical weed belonging to Toxins family. Amongst Toxins, Tetrodotoxin (TTX) contains anti–fungal activity, acetylcholinesterase inhibitory activity, anti–oxidant activity 4849505152535455565758596061626364, mast cell stabilization and membrane protection activity 65666768697071727374757677787980818283848586878889909192, anti–bacterial activity 93949596979899100101102103104105106107108109110111112113114115116117118119120121122123124125126127 and anti–cancer activity 128129130131132133134135136137138139140141142143144145, anti–hyperglycemic an anti–hyperlipidemic effects 146147148149150151152153154155156 and anti–arthritic activity, immunomodulatory activity 157158159160161162163164165166167168169170171172173 and anti–diabetic activity 174175176177178179180181182183184185186187188. Our earlier report stated that the Tetrodotoxin (TTX) has high anti–oxidant activity 189190191192193194195196197198199200201. The observations show that Tetrodotoxin (TTX) can be used for pharmaceutical applications. In this view, Tetrodotoxin (TTX) was taken and examined for its phytochemical and active principles in vitro anti–oxidant models and in silico approach for anti–histamine activity. Free radicals are atoms with unpaired electrons which can cause various diseases. Intake of vitamin E can reduce the problems associated with free radicals in the body 202203204205206207208209210. The unpaired electrons of free–radical accumulation cause oxidative stress in the body. Oxidative stress causes cell damage leading to various health issues such as chronic disease, cancer, autoimmune disorders, aging, cataract, rheumatoid arthritis, cardiovascular diseases, neurodegenerative diseases, respiratory disorders 211212213214215216217218219 and also the induced oxidative stress causes bronchial contraction by the release of cyclooxygenase and lipooxygenase in the airway that leads to bronchial asthma in human 220221222223224225226. Asthma is a chronic inflammatory lung disease that happens due to the respiratory infection triggered by the inhalation of allergens like tobacco smoke, air pollutants, genetic and environment factors 227228229230231232233 which leads to the release of histamine and leukotrienes from the mast cell in the lung. The high release of histamine due to allergic reactions is regulated by histamine H1 receptor 234235236. Histamine affects the immune response and related functions in human through H1, H2, H3 and H4 receptors activation with their intracellular signals 237238239240. The present research work demonstrates the chemotaxonomy of such valuable plant, from the genus of Tetrodotoxin (TTX). In addition, pharmaceutical applications such as in vitro anti–oxidant and in silico anti–histamine activity of their active principles as natural remedy was examined.

Details of Calculations

All calculations of molecular orbital in the base of ab are performed by Gaussian 09. In calculation process, the structure of Tetrodotoxin (TTX) molecule (Figure 1) is optimized and FT–IR and Raman wavenumbers are calculated using F/6–31G*, HF/6–31++G**, MP2/6–31G, MP2/6–31++G**, BLYP/6–31G, BLYP/6–31++G**, B3LYP/6–31G and B3LYP6–31–HEG** base. All optimized structures are adjusted with minimum energy. Harmonic vibrational wavenumbers are calculated using second degree of derivation to adjust convergence on potential surface as good as possible and to evaluate vibrational energies at zero point. In optimized structures considered in the current study, virtual frequency modes are not observed which indicates that the minimum potential energy surface is correctly chosen. The optimized geometry is calculated by minimizing the energy relative to all geometrical quantities without forcing any constraint on molecular symmetry. Calculations were performed by Gaussian 09. The current calculation is aimed to maximize structural optimization using density functional theory. The calculations of density functional theory is performed by F/6–31G*, HF/6–31++G**, MP2/6–31G, MP2/6–31++G**, BLYP/6–31G, BLYP/6–31++G**, B3LYP/6–31G and B3LYP6–31–HEG** function in which non–focal functions of Becke and correlation functions of Lee–Yang–Parr beyond the Franck–Condon approximation are used. After completion of optimization process, the second order derivation of energy is calculated as a function of core coordination and is investigated to evaluate whether the structure is accurately minimized. Vibrational frequencies used to simulate spectrums presented in the current study are derived from these second order derivatives. All calculations are performed for room temperature of 454 (K).

Section of the Tetrodotoxin (TTX) 43–93. Vibration Analysis

Analysis of vibrational spectrum of Tetrodotoxin (TTX) is performed based on theoretical simulation and FT–IR empirical spectrum and Raman empirical spectrum using density functional theory in levels of F/6–31G*, HF/6–31++G**, MP2/6–31G, MP2/6–31++G**, BLYP/6–31G, BLYP/6–31++G**, B3LYP/6–31G and B3LYP6–31–HEG**. Vibration modes of methylene, carboxyl acid and phenyl cycle are separately investigated.

C–H stretching vibrations in single replacement of benzene cycles are usually seen in band range of 3255–3505 cm–1. Weak Raman bands are at 3244 cm–1 and 3257 cm–1. C–C stretching mode is a strong Raman mode at 1199 cm–1. Raman weak band is seen at 1673 cm–1, too. Bending mode of C–H is emerged as a weak mode at 1453 cm–1 and 1252 cm–1 and a strong band at 1346 cm–1 in Raman spectrum. Raman is considerably active in the range of 1255–1505 cm–1 which 1248 cm–1 indicates this issue.

C–H skew–symmetric stretching mode of methylene group is expected at 3185 cm–1 and its symmetric mode is expected at 3054 cm–1. Skew–symmetric stretching mode of CH2 in Tetrodotoxin (TTX) has a mode in mid–range of Raman spectrum at 3155–3275 cm–1. When this mode is symmetric, it is at 3145 cm–1 and is sharp. The calculated wavenumbers of higher modes are at 3108 cm–1 and 3148 cm–1 for symmetric and skew–symmetric stretching mode of methylene, respectively.

Scissoring vibrations of CH2 are usually seen at the range of 1582–1636 cm–1 which often includes mid–range bands. Weak bands at 1595 cm–1 are scissoring modes of CH2 in Raman spectrum. Moving vibrations of methylene are usually seen at 1524 cm–1. For the investigated chemical in the current study, these vibrations are at 1394 cm–1 were calculated using density functional theory. Twisting and rocking vibrations of CH2 are seen in Raman spectrum at 970 cm–1 and 1244 cm–1, respectively, which are in good accordance with the results at 954 cm–1 and 1229 cm–1, respectively.

In a non–ionized carboxyl group (COOH), stretching vibrations of carbonyl C=O are mainly observed at the range of 1895–1943 cm–1. If dimer is considered as an intact constituent, two stretching vibrations of carbonyl for symmetric stretching are at 1785–1840 cm–1 in Raman spectrum. In the current paper, stretching vibration of carbonyl mode is at 1852 cm–1 which is a mid–range value.

Stretching and bending bands of hydroxyl can be identified by width and band intensity which in turn is dependent on bond length of Hydrogen. In dimer form of Hydrogen bond, stretching band of O–H is of a strong Raman peak at 1424 cm–1 which is due to in–plain metamorphosis mode. Out–of–plain mode of O–H group is a very strong mode of peak at 1084 cm–1 of Raman spectrum. The stretching mode of C–O (H) emerges as a mid–band of Raman spectrum at 1302 cm–1.

Lattice vibrations are usually seen at the range of 0–650 cm–1. These modes are induced by rotary and transferring vibrations of molecules and vibrations and are including Hydrogen bond. Bands with low wavenumbers of Hydrogen bond vibrations in FT–IR and Raman spectrum (Figure 2) are frequently weak, width and unsymmetrical. Rotary lattice vibrations are frequently stronger than transferring ones. Intra–molecular vibrations with low wavenumbers involving two–bands O–H …O dimer at 243 cm–1, 348 cm–1 and 407 cm–1 are attributed to a rotary moving of two molecules involving in–plain rotation of molecules against each other.

3D Simulation of (a) FT–IR spectrum and (b) Raman spectrum of Tetrodotoxin (TTX). Conclusion and Summary

Calculations of density functional theory using F/6–31G*, HF/6–31++G**, MP2/6–31G, MP2/6–31++G**, BLYP/6–31G, BLYP/6–31++G**, B3LYP/6–31G and B3LYP6–31–HEG** levels were used to obtain vibrational wavenumbers and intensities in single crystal of Tetrodotoxin (TTX). Investigation and consideration of vibrational spectrum confirm the formation of dimer cycles in the investigated crystal with carboxyl groups from each Hydrogen molecule of acid protected from adjacent molecules. The calculated vibrational spectrum which obtains from calculations of density functional theory is in good accordance with recorded empirical values which indicates successful simulation of the problem. The obtained results indicate that the results obtained from theoretical calculations are valid through comparing with empirical recorded results.

Authors are supported by an American International Standards Institute (AISI) Future Fellowship Grant FT1201009373520. We acknowledge Ms. Isabelle Villena for instrumental support and Dr. Michael N. Cocchi for constructing graphical abstract figure. We gratefully acknowledge Prof. Dr. Christopher Brownfor proof reading the manuscript.

Heidari A Brown C Study of Composition and Morphology of Cadmium Oxide (CdO) Nanoparticles for Eliminating Cancer Cells” 2015 J Nanomed Res 2 5 20 Heidari A Brown C Study of Surface Morphological, Phytochemical and Structural Characteristics of Rhodium (III) Oxide (Rh2O3) Nanoparticles” 2015 International Journal of Pharmacology, Phytochemistry and Ethnomedicine 1 1 15 19 Heidari A An Experimental Biospectroscopic Study on Seminal Plasma in Determination of Semen Quality for Evaluation of Male Infertility” 2016 Int J Adv Technol 7 007 Heidari A Extraction and Preconcentration of N–Tolyl–Sulfonyl–Phosphoramid–Saeure–Dichlorid as an Anti–Cancer Drug from Plants: A Pharmacognosy Study” 2016 J Pharmacogn Nat Prod 2 103 Heidari A A Thermodynamic Study on Hydration and Dehydration of DNA and RNA−Amphiphile 2016 Complexes”, J Bioeng Biomed Sci S: 006 Heidari A Computational Studies on Molecular Structures and Carbonyl and Ketene Groups’ Effects of Singlet and 2016 Triplet Energies of Azidoketene O=C=CH–NNN and Isocyanatoketene O=C=CH–N=C=O”, J Appl Computat Math 5 142 Heidari A Study of Irradiations to Enhance the Induces the Dissociation of Hydrogen Bonds between Peptide Chains and Transition from Helix Structure to Random Coil Structure Using ATR–FTIR, Raman and1HNMR Spectroscopies” 2016 J Biomol Res Ther 5 146 Heidari A Future Prospects of Point Fluorescence Spectroscopy, Fluorescence Imaging and Fluorescence Endoscopy in Photodynamic Therapy (PDT) for Cancer Cells” 2016 J Bioanal Biomed 8 135 Heidari A A Bio–Spectroscopic Study of DNA Density and Color Role as Determining Factor for Absorbed Irradiation in Cancer Cells”, Adv Cancer Prev 1: e102 2016 Heidari A Manufacturing Process of Solar Cells Using Cadmium Oxide (CdO) and Rhodium (III) Oxide (Rh2O3) Nanoparticles” 2016 J Biotechnol Biomater 6 125 Heidari A A Novel Experimental and Computational Approach to Photobiosimulation of Telomeric DNA/RNA: 2016 A Biospectroscopic and Photobiological Study”, J Res Development 4 144 Heidari A Biochemical and Pharmacodynamical Study of Microporous Molecularly Imprinted Polymer Selective for Vancomycin 2016 Teicoplanin, Oritavancin, Telavancin and Dalbavancin Binding”, Biochem Physiol 5 146 Heidari A Anti–Cancer Effect of UV Irradiation at Presence of Cadmium Oxide (CdO) 2016 Nanoparticles on DNA of Cancer Cells: A Photodynamic Therapy Study”, Arch Cancer Res 4 1 Heidari A Biospectroscopic Study on Multi–Component Reactions (MCRs) in Two A–Type and B–Type Conformations of Nucleic Acids to Determine Ligand Binding Modes, Binding Constant and Stability of Nucleic Acids in Cadmium Oxide (CdO) Nanoparticles–Nucleic Acids Complexes as Anti–Cancer Drugs”, Arch Cancer Res 2016 4 2 Heidari A Simulation of Temperature Distribution of DNA/RNA of Human Cancer Cells Using Time–Dependent Bio–Heat Equation and Nd: 2016 YAG Lasers”, Arch Cancer Res 4 2 Heidari A Quantitative Structure–Activity Relationship (QSAR) Approximation for Cadmium Oxide (CdO) and Rhodium (III) Oxide (Rh2O3) Nanoparticles as Anti–Cancer Drugs for the Catalytic Formation of Proviral DNA from Viral RNA Using Multiple Linear and Non–Linear Correlation Approach”, Ann Clin Lab Res 2016 4 1 Heidari A Biomedical Study of Cancer Cells DNA Therapy Using Laser Irradiations at Presence of Intelligent Nanoparticles” 2016 J Biomedical Sci 5 2 Heidari A Measurement the Amount of Vitamin 2016 J Biom Biostat D2 (Ergocalciferol), Vitamin D3 (Cholecalciferol) and Absorbable Calcium (Ca2+), Iron (II) (Fe2+), Magnesium (Mg2+), Phosphate (PO4–) and Zinc (Zn2+) in Apricot Using High–Performance Liquid Chromatography (HPLC) and Spectroscopic Techniques” 7 292 Heidari A Spectroscopy and Quantum Mechanics of the Helium Dimer 2016 (He2+), Neon Dimer (Ne2+), Argon Dimer (Ar2+), Krypton Dimer (Kr2+), Xenon Dimer (Xe2+), Radon Dimer(Rn2+) and Ununoctium Dimer (Uuo2+) Molecular Cations”, Chem Sci J 7: e112 Heidari A Human Toxicity Photodynamic Therapy Studies on DNA/RNA Complexes as a Promising New Sensitizer for the Treatment of Malignant Tumors Using Bio–Spectroscopic Techniques” 2016 J Drug Metab Toxicol 7 129 Heidari A Novel and Stable Modifications of Intelligent Cadmium Oxide (CdO) Nanoparticles as Anti–Cancer Drug in Formation of 2016 Nucleic Acids Complexes for Human Cancer Cells’ Treatment”, Biochem Pharmacol (Los Angel) 5 207 Heidari A A Combined Computational and QM/MM Molecular Dynamics Study on Boron Nitride Nanotubes (BNNTs), Amorphous Boron Nitride Nanotubes (a–BNNTs) and Hexagonal Boron Nitride Nanotubes (h–BNNTs) as Hydrogen Storage” 2016 Struct Chem Crystallogr Commun 2 1 Heidari A Pharmaceutical and Analytical Chemistry Study of Cadmium Oxide (CdO) Nanoparticles Synthesis Methods and Properties as Anti–Cancer Drug and its Effect on Human Cancer Cells”, Pharm Anal Chem Open Access 2: 113 2016 Heidari A A Chemotherapeutic and Biospectroscopic Investigation of the Interaction of Double–Standard DNA/RNA–Binding Molecules with Cadmium Oxide (CdO) and Rhodium (III) Oxide (Rh2O3) Nanoparticles as Anti–Cancer Drugs for Cancer Cells’ Treatment”, Chemo Open Access 5: e129 2016 Heidari A Pharmacokinetics and Experimental Therapeutic Study of DNA and Other Biomolecules Using Lasers: Advantages and Applications” 2016 J Pharmacokinet Exp Ther 1 005 Heidari A Determination of Ratio and Stability Constant of DNA/RNA in Human Cancer Cells and Cadmium Oxide (CdO) Nanoparticles Complexes Using Analytical Electrochemical and Spectroscopic Techniques” 2016 Insights Anal Electrochem 2 1 Heidari A Discriminate between Antibacterial and Non–Antibacterial Drugs Artificial Neutral Networks of a Multilayer Perceptron (MLP) Type Using a Set of Topological Descriptors” 2016 J Heavy Met Toxicity Dis 1 2 Heidari A Combined Theoretical and Computational Study of the Belousov–Zhabotinsky Chaotic Reaction and Curtius Rearrangement for Synthesis of Mechlorethamine 2016 Cisplatin, Streptozotocin, Cyclophosphamide, Melphalan, Busulphan and BCNU as Anti–Cancer Drugs”, Insights Med Phys 1 2 Heidari A A Translational Biomedical Approach to Structural Arrangement of Amino Acids’ 2016 Complexes: A Combined Theoretical and Computational Study”, Transl Biomed 7 2 Heidari A Ab Initio and Density Functional Theory (DFT) 2016 Studies of Dynamic NMR Shielding Tensors and Vibrational Frequencies of DNA/RNA and Cadmium Oxide (CdO) Nanoparticles Complexes in Human Cancer Cells”, J Nanomedine Biotherapeutic Discov 6: e144 Heidari A Molecular Dynamics and Monte–Carlo Simulations for Replacement Sugars in Insulin Resistance, Obesity 2016 LDL Cholesterol, Triglycerides, Metabolic Syndrome, Type 2 Diabetes and Cardiovascular Disease: A Glycobiological Study”, J Glycobiol 5: e111 Heidari A Synthesis and Study of 5–[(Phenylsulfonyl)Amino]–1,3,4–Thiadiazole–2–Sulfonamide as Potential Anti–Pertussis Drug Using Chromatography and Spectroscopy Techniques”, Transl Med (Sunnyvale) 6: e138 2016 Heidari A Nitrogen, Oxygen, Phosphorus and Sulphur Heterocyclic Anti–Cancer Nano Drugs Separation in the Supercritical Fluid of Ozone (O3) Using Soave–Redlich–Kwong (SRK) and Pang–Robinson (PR) Equations” 2016 Electronic J Biol 12 4 Heidari A An Analytical and Computational Infrared Spectroscopic Review of Vibrational Modes in Nucleic Acids” 2016 Austin J Anal Pharm Chem 3 1 1058 Heidari A Brown C 2016 Phase, Composition and Morphology Study and Analysis of Os–Pd/HfC Nanocomposites”, Nano Res Appl 2 1 Heidari A Brown C Vibrational Spectroscopic Study of Intensities and Shifts of Symmetric Vibration Modes of Ozone Diluted by Cumene” 2016 International Journal of Advanced Chemistry 4 1 5 9 Heidari A Study of the Role of Anti–Cancer Molecules with Different Sizes for Decreasing Corresponding Bulk Tumor Multiple Organs or Tissues”, Arch Can Res 2016 4 2 Heidari A Genomics and Proteomics Studies of Zolpidem, Necopidem, Alpidem, Saripidem, Miroprofen, Zolimidine, Olprinone and Abafungin as Anti–Tumor, Peptide Antibiotics, Antiviral and Central Nervous System (CNS) 2016 Drugs”, J Data Mining Genomics & Proteomics 7 125 Heidari A Pharmacogenomics and Pharmacoproteomics Studies of Phosphodiesterase-5 (PDE5) Inhibitors and Paclitaxel Albumin–Stabilized Nanoparticles as Sandwiched Anti–Cancer Nano Drugs between Two 2016 DNA/RNA Molecules of Human Cancer Cells”, J Pharmacogenomics Pharmacoproteomics 7 153 Heidari A Biotranslational Medical and Biospectroscopic Studies of Cadmium Oxide (CdO) Nanoparticles–DNA/RNA Straight and Cycle Chain Complexes as Potent Anti–Viral, Anti–Tumor and Anti–Microbial Drugs: A Clinical Approach” 2016 Transl Biomed 7 2 Heidari A A Comparative Study on Simultaneous Determination and Separation of Adsorbed Cadmium Oxide (CdO) Nanoparticles on DNA/RNA of Human Cancer Cells Using Biospectroscopic Techniques and Dielectrophoresis (DEP) 2016 Method”, Arch Can Res 4 2 Heidari A Cheminformaticsand System Chemistryof Cisplatin, Carboplatin, Nedaplatin, Oxaliplatin, Heptaplatin and Lobaplatin as Anti–Cancer Nano Drugs: 2016 A Combined Computational and Experimental Study”, J Inform Data Min 1 3 Heidari A Linear and Non–Linear Quantitative Structure–Anti–Cancer–Activity Relationship (QSACAR) Study of Hydrous Ruthenium (IV) Oxide (RuO2) Nanoparticles as Non–Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) and Anti–Cancer Nano Drugs” 2016 J Integr Oncol 5 110 Heidari A Synthesis, Characterization and Biospectroscopic Studies of Cadmium Oxide (CdO) Nanoparticles–Nucleic Acids Complexes Absence of Soluble Polymer as a Protective Agent Using Nucleic Acids Condensation and Solution Reduction Method” 2016 J Nanosci Curr Res 1 101 Heidari A Coplanarity and Collinearity of 4’–Dinonyl–2,2’–Bithiazole in One Domain of Bleomycin and Pingyangmycin to be Responsible for Binding of Cadmium Oxide (CdO) Nanoparticles to DNA/RNA Bidentate Ligands as Anti–Tumor Nano Drug” 2016 Int J Drug Dev & Res 8 007 008 Heidari A A Pharmacovigilance Study on Linear and Non–Linear Quantitative Structure (Chromatographic) Retention Relationships (QSRR) Models for the Prediction of Retention Time of Anti–Cancer Nano Drugs under Synchrotron Radiations” 2016 J Pharmacovigil 4 161 Heidari A Nanotechnology in Preparation of Semipermeable Polymers” 2016 J Adv Chem Eng 6 157 Heidari A A Gastrointestinal Study on Linear and Non–Linear Quantitative Structure (Chromatographic) Retention Relationships (QSRR) Models for Analysis 2016 5–Aminosalicylates Nano Particles as Digestive System Nano Drugs under Synchrotron Radiations”, J Gastrointest Dig Syst 6: e119 Heidari A DNA/RNA Fragmentation and Cytolysis in Human Cancer Cells Treated with Diphthamide Nano Particles Derivatives”, Biomedical Data Mining 5: e102 2016 Heidari A A Successful Strategy for the Prediction of Solubility in the Construction of Quantitative Structure–Activity Relationship (QSAR) and Quantitative Structure–Property Relationship (QSPR) under Synchrotron Radiations Using Genetic Function Approximation (GFA) Algorithm” 2016 J Mol Biol Biotechnol 1 1 Heidari A Computational Study on Molecular Structures of C20, C60, C240, C540, C960, C2160and C3840Fullerene Nano Molecules under Synchrotron Radiations Using Fuzzy Logic” 2016 J Material Sci Eng 5 282 Heidari A Graph Theoretical Analysis of Zigzag Polyhexamethylene Biguanide, Polyhexamethylene Adipamide, Polyhexamethylene Biguanide Gauze and Polyhexamethylene Biguanide Hydrochloride (PHMB) Boron Nitride Nanotubes (BNNTs) 2016 Amorphous Boron Nitride Nanotubes (a–BNNTs) and Hexagonal Boron Nitride Nanotubes (h–BNNTs)”, J Appl Computat Math 5 143 Heidari A The Impact of High Resolution Imaging on Diagnosis” 2016 Int J Clin Med Imaging 3 1000 101 Heidari A A Comparative Study of Conformational Behavior of Isotretinoin (13–Cis Retinoic Acid) and Tretinoin (All–Trans Retinoic Acid (ATRA)) Nano Particles as Anti–Cancer Nano Drugs under Synchrotron Radiations Using Hartree–Fock (HF) and Density Functional Theory (DFT) 2016 Methods”, Insights in Biomed 1 2 Heidari A Advances in Logic 2016 Operations and Computational Mathematics”, J Appl Computat Math 5 5 Heidari A Mathematical Equations in Predicting Physical Behavior” 2016 J Appl Computat Math 5 5 Heidari A Chemotherapy a Last Resort for Cancer Treatment” 2016 Chemo Open Access 5 4 Heidari A Separation and Pre–Concentration of Metal Cations–DNA/RNA Chelates Using Molecular Beam Mass Spectrometry with Tunable Vacuum Ultraviolet (VUV) Synchrotron Radiation and Various Analytical Methods”, Mass Spectrom Purif Tech 2: e101 2016 Heidari A Yoctosecond Quantitative Structure–Activity Relationship (QSAR) and Quantitative Structure–Property Relationship (QSPR) under Synchrotron Radiations Studies for Prediction of Solubility of Anti–Cancer Nano Drugs in Aqueous Solutions Using Genetic Function Approximation (GFA) Algorithm”, Insight Pharm Res 2016 1 1 Heidari A Cancer Risk Prediction and Assessment in Human Cells under Synchrotron Radiations Using Quantitative Structure Activity Relationship (QSAR) and Quantitative Structure Properties Relationship (QSPR) 2016 Studies”, Int J Clin Med Imaging 3 516 Heidari A 2016 A Novel Approach to Biology”, Electronic J Biol 12 4 Heidari A Innovative Biomedical Equipment’s for Diagnosis and Treatment” 2016 J Bioengineer & Biomedical Sci 6 2 Heidari A Integrating Precision Cancer Medicine into Healthcare, Medicare Reimbursement Changes and the Practice of Oncology: Trends in Oncology Medicine and Practices” 2016 J Oncol Med & Pract 1 2 Heidari A Promoting Convergence in Biomedical and Biomaterials Sciences and Silk Proteins for Biomedical and Biomaterials Applications: An Introduction to Materials in Medicine and Bioengineering Perspectives” 2016 J Bioengineer & Biomedical Sci 6 3 Heidari A X–Ray Fluorescence and X–Ray Diffraction Analysis on Discrete Element Modeling of Nano Powder Metallurgy Processes in Optimal Container Design” 2017 J Powder Metall Min 6 1 Heidari A Biomolecular Spectroscopy and Dynamics of Nano–Sized Molecules and Clusters as Cross–Linking–Induced Anti–Cancer and Immune–Oncology Nano Drugs Delivery in DNA/RNA of Human Cancer Cells’ Membranes under Synchrotron Radiations: A Payload–Based Perspective”, Arch Chem Res 2016 1 2 Heidari A Deficiencies in Repair of Double–Standard DNA/RNA–Binding Molecules Identified in Many Types of Solid and Liquid Tumors Oncology in Human Body for Advancing Cancer Immunotherapy Using Computer Simulations and Data Analysis: Number of Mutations in a Synchronous Tumor Varies by Age and Type of Synchronous Cancer” 2017 J Appl Bioinforma Comput Biol 6 1 Heidari A Electronic Coupling among the Five Nanomolecules Shuts Down Quantum Tunneling in the Presence and Absence of an Applied Magnetic Field for Indication of the Dimer or other Provide Different Influences on the Magnetic Behavior of Single Molecular Magnets (SMMs) as Qubits for Quantum Computing” 2017 Glob J Res Rev 4 2 Heidari A Polymorphism in Nano–Sized Graphene Ligand–Induced Transformation ofAu38–xAgx/xCux(SPh–tBu)24to Au36–xAgx/xCux(SPh–tBu)24 (x = 1–12) Nanomolecules for Synthesis of Au144–xAgx/xCux[(SR)60 2017 J Nanomater Mol Nanotechnol 6 3 (SC4)60, (SC6)60, (SC12)60, (PET)60, (p–MBA)60, (F)60, (Cl)60, (Br)60, (I)60, (At)60, (Uus)60and Heidari A Biomedical Resource Oncology and Data Mining to Enable Resource Discovery in 2017 Medical, Medicinal, Clinical, Pharmaceutical, Chemical and Translational Research and Their Applications in Cancer Research”, Int J Biomed Data Min 6 103 Heidari A Study of Synthesis, Pharmacokinetics, Pharmacodynamics, Dosing, Stability, Safety and Efficacy of Olympiadane Nanomolecules as Agent for Cancer Enzymotherapy, Immunotherapy, Chemotherapy, Radiotherapy, Hormone Therapy and Targeted Therapy under Synchrotorn Radiation” 2017 J Dev Drugs 6 154 Heidari A A Novel Approach to Future Horizon of Top Seven Biomedical Research Topics to Watch in 2017: Alzheimer's, Ebola, Hypersomnia, Human Immunodeficiency Virus (HIV), Tuberculosis (TB), Microbiome/Antibiotic Resistance and Endovascular Stroke” 2017 J Bioengineer & Biomedical Sci 7 127 Heidari A Opinion on Computational Fluid Dynamics (CFD) 2017 Technique”, Fluid Mech Open Acc 4 157 Heidari A Concurrent Diagnosis of Oncology Influence Outcomes in Emergency General Surgery for Colorectal Cancer and Multiple Sclerosis (MS) Treatment Using Magnetic Resonance Imaging (MRI) and Au329(SR)84 2017 Clusters”, J Surgery Emerg Med 1 21 Au329–xAgx(SR)84, Au144(SR)60,Au68(SR)36,Au30(SR)18, Au102(SPh)44, Au38(SPh)24, Au38(SC2H4Ph)24, Au21S(SAdm)15, Au36(pMBA)24andAu25(pMBA)18 Nano Heidari A Developmental Cell BiologyinAdult Stem CellsDeath and Autophagyto Trigger a PreventiveAllergic Reactionto Common Airborne Allergens under Synchrotron Radiation Using Nanotechnology for Therapeutic Goals in Particular Allergy Shots (Immunotherapy)”, Cell Biol (Henderson 2017 NV 6 1 Heidari A Changing Metal Powder Characteristics for Elimination of the Heavy Metals Toxicity and Diseases 2017 J Powder Metall Min in Disruption of Extracellular Matrix (ECM) Proteins Adjustment in Cancer Metastases Induced by Osteosarcoma 6 170 Chondrosarcoma, Carcinoid, Carcinoma, Ewing’s Heidari A Nanomedicine–Based Combination Anti–Cancer Therapy between Nucleic Acids and Anti–Cancer Nano Drugs in Covalent Nano Drugs Delivery Systems for Selective Imaging and Treatment of Human Brain Tumors Using Hyaluronic Acid, Alguronic Acid and Sodium Hyaluronate as Anti–Cancer Nano Drugs and Nucleic Acids Delivery under Synchrotron Radiation” 2017 Am J Drug Deliv 5 2 Heidari A Clinical Trials of Dendritic Cell Therapies for CancerExposing Vulnerabilities in Human Cancer Cells’ Metabolism and Metabolomics: New Discoveries, Unique Features Inform New Therapeutic Opportunities, Biotech's Bumpy Road to the Market and Elucidating the Biochemical Programs that Support Cancer Initiation and Progression” 2017 J Biol Med Science 1 103 Heidari A The Design Graphene–Based Nanosheets as a New Nanomaterial in Anti–Cancer Therapy and Delivery of Chemotherapeutics and Biological Nano Drugs for Liposomal Anti–Cancer Nano Drugs and Gene Delivery” 2017 Br Biomed Bull 5 305 Heidari A Integrative Approach to Biological Networks for Emerging Roles of Proteomics 2017 Genomics and Transcriptomics in the Discovery and Validation of Human Colorectal Cancer Biomarkers from DNA/RNA Sequencing Data under Synchrotron Radiation”, Transcriptomics 5: e117 Heidari A Elimination of the Heavy Metals Toxicity and Diseases 2017 in Disruption of Extracellular Matrix (ECM) Proteins and Cell Adhesion Intelligent Nanomolecules Adjustment in Cancer Metastases Using Metalloenzymes and under Synchrotron Radiation”, Lett Health Biol Sci 2 2 1 4 Heidari A Treatment of Breast Cancer Brain Metastases through a Targeted Nanomolecule Drug Delivery System Based on Dopamine Functionalized Multi–Wall Carbon Nanotubes (MWCNTs) 2017 Coated with Nano Graphene Oxide (GO) and Protonated Polyaniline (PANI) in Situ During the Polymerization of Aniline Autogenic Nanoparticles for the Delivery of Anti–Cancer Nano Drugs under Synchrotron Radiation”, Br J Res 4 3 16 Heidari A Sedative, Analgesic and Ultrasound–Mediated Gastrointestinal Nano Drugs Delivery for Gastrointestinal Endoscopic Procedure, Nano Drug–Induced Gastrointestinal Disorders and Nano Drug Treatment of Gastric Acidity” 2017 Res Rep Gastroenterol 1 1 Heidari A Synthesis,Pharmacokinetics,Pharmacodynamics,Dosing, Stability, Safety and Efficacy of Orphan Nano Drugs to Treat High Cholesterol and Related Conditions and to Prevent Cardiovascular Diseaseunder Synchrotron Radiation” 2017 J Pharm Sci Emerg Drugs 5 1 Heidari A Non–Linear Compact Proton Synchrotrons to Improve Human Cancer Cells and Tissues Treatments and Diagnostics throughParticle Therapy Acceleratorswith Monochromatic Microbeams” 2017 J Cell Biol Mol Sci 2 1 1 5 Heidari A Design of Targeted Metal Chelation Therapeutics Nanocapsules as Colloidal Carriers and Blood–Brain Barrier (BBB) Translocation to Targeted Deliver Anti–Cancer Nano Drugs into the Human Brain to Treat Alzheimer’s Disease under Synchrotron Radiation” 2017 J Nanotechnol Material Sci 4 2 1 5 Gobato R Heidari A Calculations Using Quantum Chemistry for Inorganic Molecule Simulation BeLi2SeSi” 2017 Science Journal of Analytical Chemistry 5 76 85 Heidari A Different High–Resolution Simulations of Medical, Medicinal, Clinical, Pharmaceutical and Therapeutics Oncology of Human Lung Cancer Translational Anti–Cancer Nano Drugs Delivery Treatment Process under Synchrotron and X–Ray Radiations” 2017 J Med Oncol 1 1 Heidari A A Modern Ethnomedicinal Technique for Transformation, Prevention and Treatment of Human Malignant Gliomas Tumors into Human Benign Gliomas Tumors under Synchrotron Radiation” 2017 Am J Ethnomed 4 1 10 Heidari A Active Targeted Nanoparticles for Anti–Cancer Nano Drugs Delivery across the Blood–Brain Barrier for Human Brain Cancer Treatment, Multiple Sclerosis (MS) and Alzheimer's Diseases Using Chemical Modifications of Anti–Cancer Nano Drugs or Drug–Nanoparticles through Zika Virus (ZIKV) Nanocarriers under Synchrotron Radiation” 2017 J Med Chem Toxicol 2 3 1 5 Heidari A October12,2017. Investigation of Medical, Medicinal, Clinical and Pharmaceutical Applications of Estradiol, Mestranol (Norlutin), Norethindrone (NET), Norethisterone Acetate (NETA), Norethisterone Enanthate (NETE) and Testosterone Nanoparticles as Biological Imaging, Cell Labeling, Anti–Microbial Agents and Anti–Cancer Nano Drugs in Nanomedicines Based Drug Delivery Systems for Anti–Cancer Targeting and Treatment” Parana Journal of Science and Education 3 4 10 19 Heidari A A Comparative Computational and Experimental Study on Different Vibrational Biospectroscopy Methods, Techniques and Applications for Human Cancer Cells in Tumor Tissues Simulation, Modeling, Research, Diagnosis and Treatment” 2017 Open J Anal Bioanal Chem 1 1 014 020 Heidari A Combination of DNA/RNA Ligands and Linear/Non–Linear Visible–Synchrotron Radiation–Driven N–Doped Ordered Mesoporous Cadmium Oxide (CdO) Nanoparticles Photocatalysts Channels Resulted in an Interesting Synergistic Effect Enhancing Catalytic Anti–Cancer Activity” 2017 Enz Eng 6 1 Heidari A Modern Approaches in Designing Ferritin, Ferritin Light Chain, Transferrin, Beta–2 Transferrin and Bacterioferritin–Based Anti–Cancer Nano Drugs Encapsulating Nanosphere as DNA–Binding Proteins from Starved Cells (DPS)”, Mod Appro Drug Des 2017 1 1 000504 Heidari A Potency of Human Interferon β–1a and Human Interferon β–1b in Enzymotherapy, Immunotherapy, Chemotherapy, Radiotherapy, Hormone Therapy and Targeted Therapy of Encephalomyelitis Disseminate/Multiple Sclerosis (MS) 2017 and Hepatitis A, B, C, D, E, F and G Virus Enter and Targets Liver Cells”, J Proteomics Enzymol 6 1 Heidari A Transport Therapeutic Active Targeting of Human Brain Tumors Enable Anti–Cancer Nanodrugs Delivery across the Blood–Brain Barrier (BBB) to Treat Brain Diseases Using Nanoparticles and Nanocarriers under Synchrotron Radiation” 2017 J Pharm Pharmaceutics 4 2 1 5 Heidari A Brown C Combinatorial Therapeutic Approaches to DNA/RNA and Benzylpenicillin (Penicillin G), Fluoxetine Hydrochloride (Prozac and Sarafem), Propofol (Diprivan), Acetylsalicylic Acid (ASA) (Aspirin), Naproxen Sodium (Aleve and Naprosyn) and Dextromethamphetamine Nanocapsules with Surface Conjugated DNA/RNA to Targeted Nano Drugs for Enhanced Anti–Cancer Efficacy and Targeted Cancer Therapy Using Nano Drugs Delivery Systems” 2017 Ann Adv Chem 1 2 061 069 Heidari A High–Resolution Simulations of Human Brain Cancer Translational Nano Drugs Delivery Treatment Process under Synchrotron Radiation” 2017 J Transl Res 1 1 1 3 Heidari A Investigation of Anti–Cancer Nano Drugs’ Effects’ Trend on Human Pancreas Cancer Cells and Tissues Prevention 2017 Diagnosis and Treatment Process under Synchrotron and X–Ray Radiations with the Passage of Time Using Mathematica”, Current Trends Anal Bioanal Chem 1 1 36 41 Heidari A Pros and Cons Controversy on Molecular Imaging and Dynamics of Double–Standard DNA/RNA of Human Preserving Stem Cells–Binding Nano Molecules with Androgens/Anabolic Steroids (AAS) or Testosterone Derivatives through Tracking of Helium–4 Nucleus (Alpha Particle) Using Synchrotron Radiation” 2017 Arch Biotechnol Biomed 1 1 067 0100 Heidari A Visualizing Metabolic Changes in Probing Human Cancer Cells and Tissues Metabolism Using 2017 Vivo1H or Proton NMR,13C NMR,15N NMR and31P NMR Spectroscopy and Self–Organizing Maps under Synchrotron Radiation”, SOJ Mater Sci Eng 5 2 1 6 Heidari A Cavity Ring–Down Spectroscopy (CRDS), Circular Dichroism Spectroscopy, Cold Vapour Atomic Fluorescence Spectroscopy and Correlation Spectroscopy Comparative 2017 Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation”, Enliven: Challenges Cancer Detect Ther 4 2 001 Heidari A Laser Spectroscopy, Laser–Induced Breakdown Spectroscopy and Laser–Induced Plasma Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation” 2017 Int J Hepatol Gastroenterol 3 4 079 084 Heidari A Time–Resolved Spectroscopy and Time–Stretch Spectroscopy Comparative Study on 2017 Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation”, Enliven: Pharmacovigilance and Drug Safety 4 2 001 Heidari A Overview of the Role of Vitamins in Reducing Negative Effect of Decapeptyl (Triptorelin Acetate or Pamoate Salts) 2017 Open J Anal Bioanal Chem on Prostate Cancer Cells and Tissues in Prostate Cancer Treatment Process through Transformation of Malignant Prostate Tumors into Benign Prostate Tumors under Synchrotron Radiation” 1 1 021 026 Heidari A Electron Phenomenological Spectroscopy, Electron Paramagnetic Resonance (EPR) Spectroscopy and Electron Spin Resonance (ESR) Spectroscopy Comparative 2017 J Anal Pharm Chem Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation” 4 3 1091 Austin Heidari A Therapeutic Nanomedicine Different High–Resolution Experimental Images and Computational Simulations for Human Brain Cancer Cells and Tissues Using Nanocarriers Deliver DNA/RNA to Brain Tumors under Synchrotron Radiation with the Passage of Time Using Mathematica and MATLAB” 2017 Madridge J Nano Tech. Sci 2 2 77 83 Heidari A A Consensus and Prospective Study on Restoring Cadmium Oxide (CdO) Nanoparticles Sensitivity in Recurrent Ovarian Cancer by Extending the Cadmium Oxide (CdO) Nanoparticles–Free Interval Using Synchrotron Radiation Therapy as Antibody–Drug Conjugate for the Treatment of Limited–Stage Small Cell Diverse Epithelial Cancers”, Cancer Clin Res Rep 2017 1 2 001 Heidari A A Novel and Modern Experimental Imaging and Spectroscopy Comparative 2017 Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under White Synchrotron Radiation”, Cancer Sci Res Open Access 4 2 1 8 Heidari A Different High–Resolution Simulations of Medical, Medicinal, Clinical, Pharmaceutical and Therapeutics Oncology of Human Breast Cancer Translational Nano Drugs Delivery Treatment Process under Synchrotron and X–Ray Radiations” 2017 J Oral Cancer Res 1 1 12 17 Heidari A Vibrational Decihertz (dHz), Centihertz (cHz), Millihertz (mHz), Microhertz (μHz), Nanohertz (nHz), Picohertz (pHz), Femtohertz (fHz), Attohertz (aHz), Zeptohertz (zHz) and Yoctohertz (yHz) Imaging and Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation” 2017 International Journal of Biomedicine 7 4 335 340 Heidari A Force Spectroscopy and Fluorescence Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation” 2017 EC Cancer 2 5 239 246 Heidari A Photoacoustic Spectroscopy, Photoemission Spectroscopy and Photothermal Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation” 2017 BAOJ Cancer Res Ther 3 3 045052 Heidari A J–Spectroscopy, Exchange Spectroscopy (EXSY), Nuclear Overhauser Effect Spectroscopy (NOESY) and Total Correlation Spectroscopy (TOCSY) 2017 Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, EMS Eng Sci J 1 2 006 013 Heidari A Neutron Spin Echo Spectroscopy and Spin Noise Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation” 2017 Int J Biopharm Sci 1 103 107 Heidari A Vibrational Decahertz (daHz), Hectohertz (hHz), Kilohertz (kHz), Megahertz (MHz), Gigahertz (GHz), Terahertz (THz), Petahertz (PHz), Exahertz (EHz), Zettahertz (ZHz) and Yottahertz (YHz) Imaging and Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation” 2017 Madridge J Anal Sci Instrum 2 1 41 46 Heidari A Two–Dimensional Infrared Correlation Spectroscopy, Linear Two–Dimensional Infrared Spectroscopy and Non–Linear Two–Dimensional Infrared Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time” 2018 J Mater Sci Nanotechnol 6 1 101 Heidari A Fourier Transform Infrared (FTIR) Spectroscopy, Near–Infrared Spectroscopy (NIRS) and Mid–Infrared Spectroscopy (MIRS) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time” 2018 Int J Nanotechnol Nanomed 3 1 1 6 Heidari A Infrared Photo Dissociation Spectroscopy and Infrared Correlation Table Spectroscopy Comparative 2018 Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time”, Austin Pharmacol Pharm 3 1 1011 Heidari A Novel and Transcendental Prevention, Diagnosis and Treatment Strategies for Investigation of Interaction among Human Blood Cancer Cells, Tissues, Tumors and Metastases with Synchrotron Radiation under Anti–Cancer Nano Drugs Delivery Efficacy Using MATLAB Modeling and Simulation” 2017 Madridge J Nov Drug Res 1 1 18 24 Heidari A Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation” 2018 Open Access J Trans Med Res 2 1 00026 00032 Gobato M R R Gobato R Heidari A Planting of Jaboticaba Trees for Landscape Repair of Degraded Area” 2018 Landscape Architecture and Regional Planning 3 1 1 9 Heidari A Fluorescence Spectroscopy, Phosphorescence Spectroscopy and Luminescence Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time” 2018 SM J Clin. Med. Imaging 4 1 1018 Heidari A Nuclear Inelastic Scattering Spectroscopy (NISS) and Nuclear Inelastic Absorption Spectroscopy (NIAS) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation” 2018 Int J Pharm Sci 2 1 1 14 Heidari A X–Ray Diffraction (XRD), Powder X–Ray Diffraction (PXRD) and Energy–Dispersive X–Ray Diffraction (EDXRD) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation” 2018 J Oncol Res; 2 1 1 14 Heidari A Correlation Two–Dimensional Nuclear Magnetic Resonance (NMR) 2018 (2D–NMR) (COSY) Imaging and Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, EMS Can Sci 1 1 001 Heidari A Thermal Spectroscopy, Photothermal Spectroscopy, Thermal Microspectroscopy, Photothermal Microspectroscopy, Thermal Macrospectroscopy and Photothermal Macrospectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation” 2018 SM J Biometrics Biostat 3 1 1024 Heidari A A Modern and Comprehensive Experimental Biospectroscopic Comparative Study on Human Common Cancers’ Cells, Tissues and Tumors before and after Synchrotron Radiation Therapy” 2018 Open Acc J Oncol Med 1 1 Heidari A Heteronuclear Correlation Experiments such as Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC), Heteronuclear Multiple–Quantum Correlation Spectroscopy (HMQC) and Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC) 2018 Comparative Study on Malignant and Benign Human Endocrinology and Thyroid Cancer Cells and Tissues under Synchrotron Radiation”, J Endocrinol Thyroid Res 3 1 555603 Heidari A Nuclear Resonance Vibrational Spectroscopy (NRVS), Nuclear Inelastic Scattering Spectroscopy (NISS), Nuclear Inelastic Absorption Spectroscopy (NIAS) and Nuclear Resonant Inelastic X–Ray Scattering Spectroscopy (NRIXSS) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation” 2018 Int J Bioorg Chem Mol Biol 6 1 1 5 Heidari A A Novel and Modern Experimental Approach to Vibrational Circular Dichroism Spectroscopy and Video Spectroscopy Comparative 2018 Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under White and Monochromatic Synchrotron Radiation”, Glob J Endocrinol Metab. GJEM 1 3 000514 000519 Heidari A Pros and Cons Controversy on Heteronuclear Correlation Experiments such as Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC), Heteronuclear Multiple–Quantum Correlation Spectroscopy (HMQC) and Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation” 2018 EMS Pharma J 1 1 002 008 Heidari A A Modern Comparative and Comprehensive Experimental Biospectroscopic Study on Different Types of Infrared Spectroscopy of Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation” 2018 J Analyt Molecul Tech 3 1 Heidari A Investigation of Cancer Types Using Synchrotron Technology for Proton Beam Therapy: An Experimental Biospectroscopic Comparative Study” 2018 European Modern Studies Journal 2 1 13 29 Heidari A Saturated Spectroscopy and Unsaturated Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation” 2018 Imaging J Clin Medical Sci 5 1 001 007 Heidari A Small–Angle Neutron Scattering (SANS) and Wide–Angle X–Ray Diffraction (WAXD) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation” 2018 Int J Bioorg Chem Mol Biol 6 2 1 6 Heidari A Investigation of Bladder Cancer, Breast Cancer, Colorectal Cancer, Endometrial Cancer, Kidney Cancer, Leukemia, Liver, Lung Cancer, Melanoma, Non–Hodgkin Lymphoma, Pancreatic Cancer, Prostate Cancer, Thyroid Cancer and Non–Melanoma Skin Cancer Using Synchrotron Technology for Proton Beam Therapy: An Experimental Biospectroscopic Comparative Study” 2018 Ther Res Skin Dis 1 1 Heidari A Attenuated Total Reflectance Fourier Transform Infrared (ATR–FTIR) Spectroscopy, Micro–Attenuated Total Reflectance Fourier Transform Infrared (Micro–ATR–FTIR) Spectroscopy and Macro–Attenuated Total Reflectance Fourier Transform Infrared (Macro–ATR–FTIR) Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time” 2018 International Journal of Chemistry Papers 2 1 1 12 Heidari A Mössbauer Spectroscopy, Mössbauer Emission Spectroscopy and57Fe Mössbauer Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation” 2018 Acta Scientific Cancer Biology 2 3 17 20 Heidari A Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under 2018 Synchrotron Radiation with the Passage of Time”, Organic & Medicinal Chem IJ 6 1 555676 Heidari A Correlation Spectroscopy, Exclusive Correlation Spectroscopy and Total Correlation Spectroscopy Comparative Study on Malignant and Benign Human AIDS–Related Cancers Cells and Tissues with the Passage of Time under Synchrotron Radiation” 2018 Int J Bioanal Biomed 2 1 001 007 Heidari A Biomedical Instrumentation and Applications of Biospectroscopic Methods and 2018 Techniques in Malignant and Benign Human Cancer Cells and Tissues Studies under Synchrotron Radiation and Anti–Cancer Nano Drugs Delivery”, Am J Nanotechnol Nanomed 1 1 001 009 Heidari A 2018 Vivo1H or Proton NMR,13C NMR,15N NMR and31P NMR Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Ann Biomet Biostat 1 1 1001 Heidari A Grazing–Incidence Small–Angle Neutron Scattering (GISANS) and Grazing–Incidence X–Ray Diffraction (GIXD) Comparative Study on Malignant and Benign Human Cancer Cells, Tissues and Tumors under Synchrotron Radiation”, Ann Cardiovasc Surg 2018 1 2 1006 Heidari A Adsorption Isotherms and Kinetics of Multi–Walled Carbon Nanotubes (MWCNTs), Boron Nitride Nanotubes (BNNTs), Amorphous Boron Nitride Nanotubes (a–BNNTs) and Hexagonal Boron Nitride Nanotubes (h–BNNTs) for Eliminating Carcinoma, Sarcoma, Lymphoma, Leukemia, Germ Cell Tumor and Blastoma Cancer Cells and Tissues”, Clin Med Rev Case Rep 5: 2018 201 Heidari A Correlation Spectroscopy (COSY), Exclusive Correlation Spectroscopy (ECOSY), Total Correlation Spectroscopy (TOCSY), Incredible Natural–Abundance Double–Quantum Transfer Experiment (INADEQUATE), Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC), Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC), Nuclear Overhauser Effect Spectroscopy (NOESY) and Rotating Frame Nuclear Overhauser Effect Spectroscopy (ROESY) 2018 Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Acta Scientific Pharmaceutical Sciences 2 5 30 35 Heidari A Small–Angle X–Ray Scattering (SAXS), Ultra–Small Angle X–Ray Scattering (USAXS), Fluctuation X–Ray Scattering (FXS), Wide–Angle X–Ray Scattering (WAXS), Grazing–Incidence Small–Angle X–Ray Scattering (GISAXS), Grazing–Incidence Wide–Angle X–Ray Scattering (GIWAXS), Small–Angle Neutron Scattering (SANS), Grazing–Incidence Small–Angle Neutron Scattering 2018 (GISANS), X–Ray Diffraction (XRD), Powder X–Ray Diffraction (PXRD), Wide–Angle X–Ray Diffraction (WAXD), Grazing–Incidence X–Ray Diffraction (GIXD) and Energy–Dispersive X–Ray Diffraction (EDXRD) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Oncol Res Rev, Volume 1 1 1 10 Heidari A Pump–Probe Spectroscopy and Transient Grating Spectroscopy Comparative 2018 Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation”, Adv Material Sci Engg 2 1 1 7 Heidari A Grazing–Incidence Small–Angle X–Ray Scattering (GISAXS) and Grazing–Incidence Wide–Angle X–Ray Scattering (GIWAXS) 2018 Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Insights Pharmacol Pharm Sci 1 1 1 8 Heidari A Acoustic Spectroscopy, Acoustic Resonance Spectroscopy and Auger Spectroscopy Comparative Study on Anti–Cancer Nano Drugs Delivery 2018 in Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation”, Nanosci Technol 5 1 1 9 Heidari A Osmium and Iridium Ions Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations” 2018 Nanomed Nanotechnol 3 2 000138 Heidari A Homonuclear Correlation Experiments such as Homonuclear Single–Quantum Correlation Spectroscopy (HSQC), Homonuclear Multiple–Quantum Correlation Spectroscopy (HMQC) and Homonuclear Multiple–Bond Correlation Spectroscopy (HMBC) 2018 J Proteomics Bioinform & Genomics Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation” 5 1 1024 Austin Heidari Atomic Force Microscopy Based Infrared (AFM–IR) Spectroscopy and Nuclear Resonance Vibrational Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time” 2018 J Appl Biotechnol Bioeng 5 3 142 148 Heidari A Time–Dependent Vibrational Spectral Analysis of Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation” 2018 J Cancer Oncol 2 2 000124 Heidari A Palauamine and Olympiadane Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells 2018 Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations”, Arc Org Inorg Chem Sci 3 1 Gobato R Heidari A Infrared Spectrum and Sites of Action of Sanguinarine by Molecular Mechanics and ab initio Methods” 2018 International Journal of Atmospheric and Oceanic Sciences 2 1 1 9 Heidari A Angelic Acid, Diabolic Acids, Draculin and Miraculin Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment Under Synchrotron and Synchrocyclotron Radiations” 2018 Med & Analy Chem Int J 2 1 000111 Heidari A Gamma Linolenic Methyl Ester, 5–Heptadeca–5,8,11–Trienyl 1,3,4–Oxadiazole–2–Thiol, Sulphoquinovosyl Diacyl Glycerol, Ruscogenin, Nocturnoside B, Protodioscine B, Parquisoside–B, Leiocarposide, Narangenin, 7–Methoxy Hespertin, Lupeol, Rosemariquinone, Rosmanol and Rosemadiol Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations” 2018 Int J Pharma Anal Acta 2 1 007 014 Heidari A Fourier Transform Infrared (FTIR) Spectroscopy, Attenuated Total Reflectance Fourier Transform Infrared (ATR–FTIR) Spectroscopy, Micro–Attenuated Total Reflectance Fourier Transform Infrared (Micro–ATR–FTIR) Spectroscopy, Macro–Attenuated Total Reflectance Fourier Transform Infrared (Macro–ATR–FTIR) Spectroscopy, Two–Dimensional Infrared Correlation Spectroscopy, Linear Two–Dimensional Infrared Spectroscopy, Non–Linear Two–Dimensional Infrared Spectroscopy, Atomic Force Microscopy Based Infrared (AFM–IR) Spectroscopy, Infrared Photodissociation Spectroscopy, Infrared Correlation Table Spectroscopy, Near–Infrared Spectroscopy (NIRS), Mid–Infrared Spectroscopy (MIRS), Nuclear Resonance Vibrational Spectroscopy, Thermal Infrared Spectroscopy and Photothermal Infrared Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time”, Glob Imaging Insights 2018 3 2 1 14 Heidari A Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC) and Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC) 2018 Comparative Study on Malignant and Benign Human Cancer Cells, Tissues and Tumors under Synchrotron and Synchrocyclotron Radiations”, Chronicle of Medicine and Surgery 2 3 144 156 Heidari A Tetrakis [3, 5–bis (Trifluoromethyl) Phenyl] Borate (BARF)–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules” 2018 Medical Research and Clinical Case Reports 2 1 113 126 Heidari A Sydnone, Münchnone, Montréalone, Mogone, Montelukast, Quebecol and Palau’ amine–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) 2018 Nano Molecules”, Sur Cas Stud Op Acc J 1 3 Heidari A Fornacite, Orotic Acid, Rhamnetin, Sodium Ethyl Xanthate (SEX) and Spermine (Spermidine or Polyamine) Nanomolecules Incorporation into the Nanopolymeric Matrix (NPM)” 2018 International Journal of Biochemistry and Biomolecules 4 1 1 19 Heidari A Gobato R Putrescine, Cadaverine, Spermine and Spermidine–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules” 2018 Parana Journal of Science and Education (PJSE)–v.4, n.5, (1–14) Heidari A Cadaverine (1,5–Pentanediamine or Pentamethylenediamine), Diethyl Azodicarboxylate (DEAD or DEADCAT) and Putrescine (Tetramethylenediamine) Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells 2018 Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations”, Hiv and Sexual Health Open Access Open Journal 1 1 4 11 Heidari A Improving the Performance of Nano–Endofullerenes in Polyaniline Nanostructure–Based Biosensors by Covering Californium Colloidal Nanoparticles with Multi–Walled Carbon Nanotubes” 2018 Journal of Advances in Nanomaterials 3 1 1 28 Gobato R Heidari A Molecular Mechanics and Quantum Chemical Study on Sites of Action of Sanguinarine Using Vibrational Spectroscopy Based on Molecular Mechanics and Quantum Chemical Calculations” 2018 Malaysian Journal of Chemistry 20 1 1 23 Heidari A Vibrational Biospectroscopic Studies on Anti–cancer Nanopharmaceuticals (Part I)” 2018 Malaysian Journal of Chemistry 20 1 33 73 Heidari A Vibrational Biospectroscopic Studies on Anti–cancer Nanopharmaceuticals (Part II)” 2018 Malaysian Journal of Chemistry 20 1 74 117 Heidari A Uranocene (U(C8H8)2) and Bis (Cyclooctatetraene) Iron (Fe(C8H8)2or Fe (COT)2)–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules”, Chemistry Reports 2018 1 2 1 16 Heidari A Biomedical Systematic and Emerging Technological Study on Human Malignant and Benign Cancer Cells and Tissues Biospectroscopic Analysis under Synchrotron Radiation”, Glob Imaging Insights 2018 3 3 1 7 Heidari A Deep–Level Transient Spectroscopy and X–Ray Photoelectron Spectroscopy (XPS) 2018 Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation”, Res Dev Material Sci 7 2 000659 Heidari A C70–Carboxyfullerenes Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations”, Glob Imaging Insights 2018 3 3 1 7 Heidari A The Effect of Temperature on Cadmium Oxide (CdO) Nanoparticles Produced by Synchrotron Radiation in the Human Cancer Cells, Tissues and Tumors” 2018 International Journal of Advanced Chemistry 6 2 140 156 Heidari A A Clinical and Molecular Pathology Investigation of Correlation Spectroscopy (COSY), Exclusive Correlation Spectroscopy (ECOSY), Total Correlation Spectroscopy (TOCSY), Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC) and Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC) Comparative Study on Malignant and Benign Human Cancer Cells, Tissues and Tumors under Synchrotron and Synchrocyclotron Radiations Using Cyclotron versus Synchrotron, Synchrocyclotron and the Large Hadron Collider (LHC) for Delivery of Proton and Helium Ion (Charged Particle) Beams for Oncology Radiotherapy” 2018 European Journal of Advances in Engineering and Technology 5 7 414 426 Heidari A Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations” 2018 J Oncol Res; 1 1 1 20 Heidari A Use of Molecular Enzymes in the Treatment of Chronic Disorders” 2018 Canc Oncol Open Access J 1 1 12 15 Heidari A Vibrational Biospectroscopic Study and Chemical Structure Analysis of Unsaturated Polyamides Nanoparticles as Anti–Cancer Polymeric Nanomedicines Using Synchrotron Radiation” 2018 International Journal of Advanced Chemistry 6 2 167 189 Heidari A “Adamantane Irene Naftazone and Pyridine–Enhanced Precatalyst Preparation Stabilization and Initiation (PEPPSI) 2018 Nano Molecules”, Madridge J Nov Drug Res 2 1 61 67 Heidari A Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC) and Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC) 2018 Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation”, Madridge J Nov Drug Res 2 1 68 74 Heidari A Gobato R A Novel Approach to Reduce Toxicities and to Improve Bioavailabilities of DNA/RNA of Human Cancer Cells–Containing Cocaine (Coke), Lysergide (Lysergic Acid Diethyl Amide or LSD), Δ–Tetrahydrocannabinol (THC) [(–)–trans–Δ–Tetrahydrocannabinol], Theobromine (Xantheose), Caffeine, Aspartame (APM) (NutraSweet) and Zidovudine (ZDV) (Azidothymidine (AZT)) as Anti–Cancer Nano Drugs by Coassembly of Dual Anti–Cancer Nano Drugs to Inhibit DNA/RNA of Human Cancer Cells Drug Resistance” 2018 Parana Journal of Science and Education 4 6 1 17 Heidari A Gobato R Ultraviolet Photoelectron Spectroscopy (UPS) and Ultraviolet–Visible (UV–Vis) Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation” 2018 Parana Journal of Science and Education 4 6 18 33 Gobato R Heidari A Mitra A The Creation of C13H20BeLi2SeSi. The Proposal of a Bio–Inorganic Molecule, Using Ab Initio Methods for the Genesis of a Nano Membrane”, Arc Org Inorg Chem Sci 2018 3 4 000167 Gobato R Heidari A Mitra A Using the Quantum Chemistry for Genesis of a Nano Biomembrane with a Combination of the Elements 2018 Be, Li, Se, Si, C Gobato R Heidari A Using the Quantum Chemistry for Genesis of a Nano Biomembrane with a 2018 Combination of the Elements Be, Li, Se, Si, C and H”, J Nanomed 7 4 241 252 Heidari A Bastadins and Bastaranes–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules”, Glob Imaging Insights 2018 3 4 1 7 Heidari A Fucitol, Pterodactyladiene, DEAD or DEADCAT (DiEthyl AzoDiCArboxylaTe), Skatole, the NanoPutians, Thebacon, Pikachurin, Tie Fighter, Spermidine and Mirasorvone Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations”, Glob Imaging Insights 2018 3 4 1 8 Dadvar E Heidari A A Review on Separation Techniques of Graphene Oxide (GO)/Base on Hybrid Polymer Membranes for Eradication of Dyes and Oil Compounds: Recent Progress in Graphene Oxide (GO)/Base on Polymer Membranes–Related Nanotechnologies”, Clin Med Rev Case Rep 5: 228 2018 Heidari A Gobato R First–Time Simulation of Deoxyuridine Monophosphate (dUMP) (Deoxyuridylic Acid or Deoxyuridylate) and Vomitoxin (Deoxynivalenol (DON)) ((3α,7α)–3,7,15–Trihydroxy–12,13–Epoxytrichothec–9–En–8–One)–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations” 2018 Parana Journal of Science and Education 4 46 67 Heidari A Buckminsterfullerene (Fullerene), Bullvalene, Dickite and Josiphos Ligands Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Hematology and Thromboembolic Diseases Prevention, Diagnosis and Treatment under Synchrotron and Synchrocyclotron Radiations”, Glob Imaging Insights 2018 3 4 1 7 Heidari A Fluctuation X–Ray Scattering (FXS) and Wide–Angle X–Ray Scattering (WAXS) 2018 Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Glob Imaging Insights, Volume 3 4 1 7 Heidari A A Novel Approach to Correlation Spectroscopy (COSY), Exclusive Correlation Spectroscopy (ECOSY), Total Correlation Spectroscopy (TOCSY), Incredible Natural–Abundance Double–Quantum Transfer Experiment (INADEQUATE), Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC), Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC), Nuclear Overhauser Effect Spectroscopy (NOESY) and Rotating Frame Nuclear Overhauser Effect Spectroscopy (ROESY) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Glob Imaging Insights 2018 3 5 1 9 Heidari A Terphenyl–Based Reversible Receptor with Rhodamine, Rhodamine–Based Molecular Probe, Rhodamine–Based Using the Spirolactam Ring Opening, Rhodamine B with Ferrocene Substituent, Calix[4]Arene–Based Receptor, Thioether + Aniline–Derived Ligand Framework Linked to a Fluorescein Platform 2018 Mercuryfluor–1 (Flourescent Probe), N,N’–Dibenzyl–1,4,10, 13–Tetraraoxa–7,16–Diazacyclooctadecane and Terphenyl–Based Reversible Receptor with Pyrene and Quinoline as the Fluorophores–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules”, Glob Imaging Insights 3 5 1 9 Heidari A Small–Angle X–Ray Scattering (SAXS), Ultra–Small Angle X–Ray Scattering (USAXS), Fluctuation X–Ray Scattering (FXS), Wide–Angle X–Ray Scattering (WAXS), Grazing–Incidence Small–Angle X–Ray Scattering (GISAXS), Grazing–Incidence Wide–Angle X–Ray Scattering (GIWAXS), Small–Angle Neutron Scattering (SANS), Grazing–Incidence Small–Angle Neutron Scattering 2018 (GISANS), X–Ray Diffraction (XRD), Powder X–Ray Diffraction (PXRD), Wide–Angle X–Ray Diffraction (WAXD),Grazing–Incidence X–Ray Diffraction (GIXD) and Energy–Dispersive X–Ray Diffraction (EDXRD) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Glob Imaging Insights, Volume 3 5 1 10 Heidari A Nuclear Resonant Inelastic X–Ray Scattering Spectroscopy (NRIXSS) and Nuclear Resonance Vibrational Spectroscopy (NRVS) 2018 Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Glob Imaging Insights, Volume 3 5 Heidari A Small–Angle X–Ray Scattering (SAXS) and Ultra–Small Angle X–Ray Scattering (USAXS) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Glob Imaging Insights 2018 3 5 1 7 Heidari A Curious Chloride (CmCl3) and Titanic Chloride (TiCl4)–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules for Cancer Treatment and Cellular Therapeutics” 2018 J. Cancer Research and Therapeutic Interventions, Volume 1 1 01 10 Gobato R Gobato M R R Heidari A Mitra A Spectroscopy and Dipole Moment of the Molecule C13H20BeLi2SeSi via Quantum Chemistry Using Ab Initio 2018 Hartree–Fock Method in the Base Set CC–pVTZ and 6–311G**(3df, 3pd)”, Arc Org Inorg Chem Sci 3 5 402 409 Heidari A C60and C70–Encapsulating Carbon Nanotubes Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations”, Integr Mol Med 2018 5 3 1 8 Heidari A 2018 Two–Dimensional (2D)1H or Proton NMR,13C NMR,15N NMR and31P NMR Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time”, Glob Imaging Insights 3 6 1 8 Heidari A FT–Raman Spectroscopy, Coherent Anti–Stokes Raman Spectroscopy (CARS) and Raman Optical Activity Spectroscopy (ROAS) 2018 Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation”, Glob Imaging Insights, Volume 3 6 1 8 Heidari A A Modern and Comprehensive Investigation of Inelastic Electron Tunneling Spectroscopy (IETS) and Scanning Tunneling Spectroscopy on Malignant and Benign Human Cancer Cells, Tissues and Tumors through Optimizing Synchrotron Microbeam Radiotherapy for Human Cancer Treatments and Diagnostics: An Experimental Biospectroscopic Comparative Study”, Glob Imaging Insights 2018 3 6 1 8 Heidari A A Hypertension Approach to Thermal Infrared Spectroscopy and Photothermal Infrared Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time”, Glob Imaging Insights 2018 3 6 1 8 Heidari A Incredible Natural–Abundance Double–Quantum Transfer Experiment (INADEQUATE), Nuclear Overhauser Effect Spectroscopy (NOESY) and Rotating Frame Nuclear Overhauser Effect Spectroscopy (ROESY) 2018 Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Glob Imaging Insights 3 6 1 8 Heidari A 2–Amino–9–((1S, 3R, 4R)–4–Hydroxy–3–(Hydroxymethyl)–2–Methylenecyclopentyl)–1H–Purin–6(9H)–One, 2–Amino–9–((1R, 3R, 4R)–4–Hydroxy–3–(Hydroxymethyl)–2–Methylenecyclopentyl)–1H–Purin–6(9H)–One, 2–Amino–9–((1R, 3R, 4S)–4–Hydroxy–3–(Hydroxymethyl)–2–Methylenecyclopentyl)–1H–Purin–6(9H)–One and 2–Amino–9–((1S, 3R, 4S)–4–Hydroxy–3–(Hydroxymethyl)–2–Methylenecyclopentyl)–1H–Purin–6(9H)–One–Enhanced Precatalyst Preparation Stabilization and Initiation Nano Molecules”, Glob Imaging Insights 2018 3 6 19 Gobato R Gobato M R R Heidari A Mitra A Spectroscopy and Dipole Moment of the Molecule C13H20BeLi2SeSi via Quantum Chemistry Using Ab Initio 2018 Hartree–Fock Method in the Base Set CC–pVTZ and 6–311G**(3df, 3pd)”, American Journal of Quantum Chemistry and Molecular Spectroscopy 2 1 9 17 Heidari A Production of Electrochemiluminescence (ECL) Biosensor Using Os–Pd/HfC Nanocomposites for Detecting and Tracking of Human Gastroenterological Cancer Cells, Tissues and Tumors” 2018 Int J Med Nano Res 5 022 034 Heidari A Enhancing the Raman Scattering for Diagnosis and Treatment of Human Cancer Cells, Tissues and Tumors Using Cadmium Oxide (CdO) 2018 Nanoparticles”, J Toxicol Risk Assess 4 012 025 Heidari A Human Malignant and Benign Human Cancer Cells and Tissues Biospectroscopic Analysis under Synchrotron Radiation Using Anti–Cancer Nano Drugs Delivery”, Integr Mol Med 2018 5 5 1 13 Heidari A Analogous Nano Compounds of the Form M(C8H8)2Exist for M = (Nd 2018 Yb)–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules”, Integr Mol Med 5 5 1 8 Tb, Pu, Pa, Np, Th, and Heidari A Hadron Spectroscopy, Baryon Spectroscopy and Meson Spectroscopy Comparative 2018 Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Integr Mol Med 5 5 1 8 Gobato R Gobato M R R Heidari A Raman Spectroscopy Study of the Nano Molecule C13H20BeLi2SeSi Using ab initio and 2019 Hartree–Fock Methods in the Basis Set CC–pVTZ and 6–311G** (3df, 3pd)”, International Journal of Advanced Engineering and Science 7 1 14 35 Heidari A Gobato R Evaluating the Effect of Anti–Cancer Nano Drugs Dosage and Reduced Leukemia and Polycythemia Vera Levels 2018 on Trend of the Human Blood and Bone Marrow Cancers under Synchrotron Radiation”, Trends in Res, Volume 2 1 1 8 Heidari A Gobato R Assessing the Variety of Synchrotron 2019 Synchrocyclotron and LASER Radiations and Their Roles and Applications in Human Cancer Cells, Tissues and Tumors Diagnosis and Treatment”, Trends in Res, Volume 2 1 1 8 Heidari A Gobato R Pros and Cons Controversy on Malignant Human Cancer Cells, Tissues and Tumors Transformation Process to Benign Human Cancer Cells, Tissues and Tumors”, Trends in Res 2019 2 1 1 8 Heidari A Gobato R Three–Dimensional (3D) Simulations of Human Cancer Cells, Tissues and Tumors for Using in Human Cancer Cells, Tissues and Tumors Diagnosis and Treatment as a Powerful Tool 2019 in Human Cancer Cells, Tissues and Tumors Research and Anti–Cancer Nano Drugs Sensitivity and Delivery Area Discovery and Evaluation”, Trends in Res, Volume 2 1 1 8 Heidari A Gobato R Investigation of Energy Production by Synchrotron, Synchrocyclotron and LASER Radiations in Human Cancer Cells, Tissues and Tumors and Evaluation of Their Effective on Human Cancer Cells, Tissues and Tumors Treatment Trend”, Trends in Res 2019 2 1 1 8 Heidari A Gobato R High–Resolution Mapping of DNA/RNA Hypermethylation and Hypomethylation 2019 Process in Human Cancer Cells, Tissues and Tumors under Synchrotron Radiation”, Trends in Res, Volume 2 2 1 9 Heidari A A Novel and Comprehensive Study on Manufacturing and Fabrication Nanoparticles Methods and Techniques for Processing Cadmium Oxide (CdO) Nanoparticles Colloidal Solution”, Glob Imaging Insights 2019 4 1 1 8 Heidari A A Combined Experimental and Computational Study on the Catalytic Effect of Aluminum Nitride Nanocrystal (AlN) on the Polymerization of Benzene, Naphthalene, Anthracene, Phenanthrene, Chrysene and Tetracene”, Glob Imaging Insights 2019 4 1 1 8 Heidari A Novel Experimental and Three–Dimensional (3D) Multiphysics Computational Framework of Michaelis–Menten Kinetics for Catalyst Processes Innovation, Characterization and Carrier Applications”, Glob Imaging Insights 2019 4 1 1 8 Heidari A The Hydrolysis Constants of Copper (I) (Cu+) and Copper (II) (Cu2+) in Aqueous Solution as a Function of pH Using a Combination of pH Measurement and Biospectroscopic Methods and Techniques”, Glob Imaging Insights 2019 4 1 1 8 Heidari A Vibrational Biospectroscopic Study of Ginormous Virus–Sized Macromolecule andPolypeptideMacromolecule as Mega Macromolecules Using Attenuated Total Reflectance–Fourier Transform Infrared (ATR–FTIR) Spectroscopy and Mathematica 11.3”, Glob Imaging Insights 2019 4 1 1 8 Heidari A Three–Dimensional (3D) Imaging Spectroscopy of Carcinoma 2019 4 1 1 9 Sarcoma, Leukemia, Lymphoma, Multiple Myeloma, Melanoma, Brain Gobato R Gobato M R R Heidari A Mitra A New Nano–Molecule Kurumi–C13H20BeLi2SeSi/C13H19BeLi2SeSi, and Raman Spectroscopy Using ab initio 2019 Hartree–Fock Method in the Base Set CC–pVTZ and 6–311G** (3df, 3pd)”, J Anal Pharm Res 8 1 1 6 Heidari A Esposito J Caissutti A The Importance of Attenuated Total Reflectance Fourier Transform Infrared (ATR–FTIR) and Raman Biospectroscopy of Single–Walled Carbon Nanotubes (SWCNT) and Multi–Walled Carbon Nanotubes (MWCNT) in Interpreting Infrared and Raman Spectra of Human Cancer Cells, Tissues and Tumors” 2019 Oncogen 2 2 1 21 Heidari A Esposito J Caissutti A 2019 Study of Anti–Cancer Properties of Thin Layers of Cadmium Oxide (CdO) Nanostructure”,Int J Analyt Bioanalyt Methods 1 1 20 A Heidari Gobato 2019 Sci Lett Evidence of Tornado Storm Hit the Counties of Rio Branco do Ivaí and Rosario de Ivaí 7 1 9 Southern Brazil” Heidari A Esposito J A Caissutti, “The Quantum Entanglement Dynamics Induced by Non–Linear Interaction between a Moving Nano Molecule and a Two–Mode Field with Two–Photon Transitions Using Reduced Von Neumann Entropy and Jaynes–Cummings Model for Human Cancer Cells, Tissues and Tumors Diagnosis” 2019 Int J Crit Care Emerg Med 5 2 071 084 Heidari A Mechanism of Action and Their Side Effects at a Glance Prevention, Treatment and 2019 Management of Immune System and Human Cancer Nano Chemotherapy”, Nanosci Technol 6 1 1 4 Heidari A Esposito J Caissutti A The Importance of Quantum Hydrodynamics (QHD) Approach to Single–Walled Carbon Nanotubes (SWCNT) and Multi–Walled Carbon Nanotubes (MWCNT) 2019 in Genetic Science”, SCIOL Genet Sci 2 1 113 129 Heidari A Esposito J Caissutti A Palytoxin Time–Resolved Absorption and Resonance FT–IR and Raman Biospectroscopy and Density Functional Theory (DFT) 2019 Investigation of Vibronic–Mode Coupling Structure in Vibrational Spectra Analysis”, J Pharm Drug Res 3 1 150 170 Heidari A Esposito J Caissutti A Aplysiatoxin Time–Resolved Absorption and Resonance FT–IR and Raman Biospectroscopy and Density Functional Theory (DFT) 2019 Investigation of Vibronic–Mode Coupling Structure in Vibrational Spectra Analysis”, J J Chem Sci Eng 2 2 70 89 Heidari A Esposito J Caissutti A Cyanotoxin Time–Resolved Absorption and Resonance FT–IR and Raman Biospectroscopy and Density Functional Theory (DFT) Investigation of Vibronic–Mode Coupling Structure in Vibrational Spectra Analysis” 2019 British Journal of Medical and Health Research 6 4 1 41 Heidari A Potential and Theranostics Applications of Novel Anti–Cancer Nano Drugs Delivery Systems in Preparing for Clinical Trials of Synchrotron Microbeam Radiation Therapy (SMRT) and Synchrotron Stereotactic Radiotherapy (SSRT) for Treatment of Human Cancer Cells, Tissues and Tumors Using Image Guided Synchrotron Radiotherapy (IGSR)” 2019 Ann Nanosci Nanotechnol 3 1 1006 1019 Heidari A Clinical and Medical Pros and Cons of Human Cancer Cells’ Enzymotherapy, Immunotherapy, Chemotherapy, Radiotherapy, Hormone Therapy and Targeted Therapy Process under Synchrotron Radiation: A Case Study on Mechanism of Action and Their Side Effects” 2019 Parana Journal of Science and Education 5 3 1 23 Heidari A The Importance of the Power 2019 in CMOS Inverter Circuit of Synchrotron and Synchrocyclotron Radiations Using 50 (nm) and 100 (nm) Technologies and Reducing the Voltage of Power Supply”, Radiother Oncol Int 1 1 1002 1015 Gobato R Gobato M R R Heidari A Mitra A Spectroscopy and Dipole Moment of the Molecule C13H20BeLi2SeSi Via Quantum Chemistry Using Ab initio 2018 Hartree–Fock Method in the Base Set CC–pVTZ and 6–311G** (3df, 3pd)”, American Journal of Quantum Chemistry and Molecular Spectroscopy 2 1 9 17 Heidari A Esposito J Caissutti A Anatoxin–a and Anatoxin–a(s) Time–Resolved Absorption and Resonance FT–IR and Raman Biospectroscopy and Density Functional Theory (DFT) Investigation of Vibronic–Mode Coupling Structure in Vibrational Spectra Analysis” 2019 Saudi J Biomed Res 4 4 174 194 Heidari A Esposito J Caissutti A Alpha–Conotoxin, Omega–Conotoxin and Mu–Conotoxin Time–Resolved Absorption and Resonance FT–IR and Raman Biospectroscopy and Density Functional Theory (DFT) Investigation of Vibronic–Mode Coupling Structure in Vibrational Spectra Analysis” 2019 International Journal of Advanced Chemistry 7 1 52 66