Research Topic · Peer-Reviewed

Bone Cells

Bone cells are the specialized cell populations that build, maintain, sense, and resorb the mineralized connective tissue of the skeleton. The principal types are osteoblasts, which synthesize and deposit the collagenous osteoid matrix and direct its mineralization; osteocytes, terminally differentiated osteoblasts …

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 64× across the literature 🗓 Reviewed June 2026

Overview

Bone cells are the specialized cell populations that build, maintain, sense, and resorb the mineralized connective tissue of the skeleton. The principal types are osteoblasts, which synthesize and deposit the collagenous osteoid matrix and direct its mineralization; osteocytes, terminally differentiated osteoblasts embedded within the matrix that act as mechanosensors and orchestrate remodelling through their canalicular network; osteoclasts, multinucleated cells of hematopoietic origin that resorb bone; and bone-lining cells and skeletal stem or progenitor cells that replenish the osteogenic lineage. Their coordinated activity governs bone modelling during growth and continuous remodelling thereafter, balancing formation against resorption to regulate skeletal mass, calcium homeostasis, and structural integrity. Disturbance of this balance underlies osteoporosis, altered trabecular and marginal bone architecture, and pathological remodelling. Research relevant to this area includes calcium orthophosphate scaffolds for bone tissue engineering, longitudinal study of marginal bone levels and trabecular structure, primary bone tumours such as periosteal osteosarcoma, and biomaterial strategies to support osteogenesis and implant integration. Such work bridges cell biology, biomaterials, and clinical skeletal medicine. The journal publishes peer-reviewed research on bone cell biology, mineralized-tissue structure, regenerative scaffolds, and skeletal pathology.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2017

Canine Periosteal Osteosarcoma

Noronha de Toledo GabrielaCorresponding author
Department of Clinic and Veterinary Surgery, School of Agricultural and Veterinary Sciences (FCAV), Universidade Estadual Paulista – UNESP, Campus Jaboticabal, SP, Brazil.
Exact topic Veterinary Healthcare Cited by 2 doi:10.14302/issn.2575-1212.jvhc-17-1574

How this research is being cited

The 12 articles above have been cited 64 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Bone Cells, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Advanced Cytology.

Journal editorial board
Krzysztof Marycz · Poland MARIA VIOLETTA BRUNDO · Italy

This page summarises published research for orientation; it is not medical or professional advice.